Association between smoking status and subclinical coronary atherosclerosis in asymptomatic Korean individuals

• DOI: 10.4178/epih.e2024064
• Publication Date: 2024-07-23T00:50:50Z
• Authors: Hyeji Lee; Jinhee Ha; Kyung Sun Park; Young-Jee Jeon; Sangwoo Park; Soe Hee Ann; Yong-Giun Kim; Yongjik Lee; Woon Jung Kwon; Seong Hoon Choi; Seungbong Han; Gyung-Min Park
• Keywords: Subclinical infection; Coronary atherosclerosis; Association (psychology)

OBJECTIVESIn this study, we sought to evaluate the association between smoking status and subclinical coronary atherosclerosis, as detected by computed tomography angiography (CCTA), in asymptomatic individuals. METHODSWe retrospectively analyzed 9,285 participants (mean age, 53.7±8.0 years; 6,017 [64.8%] male) with no history of artery disease (CAD) who had undergone self-referred CCTA. Of these participants, 4,333 (46.7%) were considered never smokers, 2,885 (31.1%) former 2,067 (22.3%) current smokers. We assessed degree characteristics atherosclerosis using CCTA, obstructive CAD defined a diameter stenosis at least 50%. RESULTSCompared never-smokers, smokers exhibited significant differences probabilities CAD, any plaque, calcified or mixed determined adjusted odds ratios (aORs; p>0.05 for all). However, risk non-calcified plaque was significantly higher (aOR, 1.34; 95% confidence interval [CI], 1.00 1.78; p=0.048). Current rates 1.46; CI, 1.10 1.96; p=0.010), 1.41; 1.20 1.65; p<0.001), 1.32; 1.13 1.55; p=0.001), 1.72; 1.28 2.32; 2.00; 1.39 2.86; p<0.001) compared CONCLUSIONSThis cross-sectional study revealed on Additionally, demonstrated an indicating elevated cardiovascular risk.