Risk Factors for Severe Rift Valley Fever Infection in Kenya, 2007

• DOI: 10.4269/ajtmh.2010.09-0293
• Publication Date: 2010-08-03T19:11:25Z
• Authors: Amwayi S. Anyangu; M. Kariuki Njenga; Janusz T. Paweska; Edith R. Lederman; David Mutonga; Shahnaaz K. Sharif; Mark Katz; David Schnabel; Patrick M. Nguku; L. Hannah Gould; Daniel R. Feikin; Allen Hightower; Carol Y. Rao; Jared O. Omolo; Robert F. Breiman
• Keywords: Rift Valley Fever

A large Rift Valley fever (RVF) outbreak occurred in Kenya from December 2006 to March 2007. We conducted a study define risk factors associated with infection and severe disease. total of 861 individuals 424 households were enrolled. Two hundred two participants (23%) had serologic evidence acute RVF infection. Of these, 52 (26%) disease characterized by hemorrhagic manifestations or death. Independent for consuming handling products sick animals (odds ratio [OR] = 2.53, 95% confidence interval [CI] 1.78-3.61, population attributable percentage [PAR%] 19%) being herds person (OR 1.77, CI 1.20-2.63, PAR% 11%). Touching an aborted animal fetus was 3.83, 1.68-9.07, 14%). Consuming death 3.67, 1.07-12.64, 47%). Exposures related contact infection, whereas exposures mosquitoes not independent factors.