Early Detection of Endocervical Adenocarcinoma and Adenocarcinoma in Situ: Role of PAP Smear and HPV Screening Test

• DOI: 10.4274/cjms.2024.2024-39
• Publication Date: 2024-08-29T13:27:58Z
• Authors: Süheyla Ekemen; Serkan Erkanlı
• Keywords: Pap test

BACKGROUND/AIMS: Endocervical adenocarcinoma (ECA) accounts for 25% of cervical cancers and is clinically more aggressive than squamous cell carcinoma (SCC).Similarly, SCC ECA can be treated without the formation invasive tumors if precursor lesions are identified accordingly.The objective this study to analyze effectiveness screening tests in detection endocervical situ (AIS), which represents a lesion ECA. MATERIALS AND METHODS:The comprised total 121 cases, including 83 cases 38 AIS, diagnosed through histopathologically examination between 2020 2023 at our center.The clinical history, cytological findings, results high-risk human papillomavirus (hrHPV) test, other pathological findings from pathology reports patients aged 26 84 years were subjected analysis. RESULTS:A 22.2% center during period ECA.The mean age was 48.6 while that AIS 39 years.A positive association observed HPV 94% cases.Among 56.6% had not undergone screening, 88% an hrHPV test.A 33 with underwent 31 exhibited abnormalities smear.All 13 tested hrHPV.A biopsy performed based on combined evaluation PAP smear test results. CONCLUSION:Our emphasizes early stage, achieving success rate 96.9%.