Prediabetes and Cardiovascular Parameters in Obese Children and Adolescents

• DOI: 10.4274/jcrpe.2248
• Publication Date: 2016-03-01T14:48:20Z
• Authors: Beray Selver Ekli...; Mehmet Emre Atabek; Nesibe Akyürek; Hayrullah Alp
• Keywords: Prediabetes; Lipid Profile

Objective: In this study, our aim was to determine cardiovascular risk and cardiac function in prediabetic obese children adolescents. Methods:The study conducted on 198 adolescents 6-18 years of age.Anthropometric measurements, blood pressure oral glucose tolerance test, lipid profile, HbA1c levels patients were assessed.Prediabetes defined according American Diabetes Association criteria.Left ventricular mass index (LVMi), carotid intima-media thickness (c-IMT), tissue Doppler measurements records used.Results: LVMi found be significantly higher the prediabetes group (p=0.03).There no statistically significant differences right between non-prediabetic groups.Left group: LVEEM (left E/e ratio) (p=0.04);LVEM myocardial velocity cm/s) (p=0.035).LVMi positively correlate with triglyceride level, diastolic pressure, waist circumference, body weight standard deviation score negatively high-density lipoprotein cholesterol (p=0.043, r=0.15; p=0.039, p=0.025, r=0.17; p=0.009, r=0.19; p=0.038, r=-0.15,respectively).LVEM correlated (p=0.046,r=0.15) systolic (p=0.035,r=0.15).In linear regression analysis for clinical factors, fasting level best predictor LVEM. Conclusion:In deterioration shown.We recommend determining dysfunction at early stages