The effect of quince leaf (<i>Cydonia oblonga</i> miller) decoction on testes in hypercholesterolemic rabbits: A pilot study

• DOI: 10.4314/ajtcam.v10i2.12
• Publication Date: 2013-01-18T15:03:28Z
• Authors: H Ashrafi; K Ghabili; A Alihemmati; A Jouyban; MM Shoja; S Aslanabadi; FH Adl; H, Ghavimi; L Hajhosseini
• Keywords: Decoction; Germinal epithelium

Current medical literature lacks any evidence of the protective effects quince leaf on testes. Therefore, aim present study was to assess effect (Cydonia oblonga Miller) decoction testicular injury and impaired spermatogenesis induced by hypercholesterolemia in rabbits. Eleven mature New Zealand white male rabbits were randomly divided into three groups: group 1 (hypercholesterolemia, n=3), 2 (hypercholesterolemia plus treatment, n=6), 3 (control, n=2). Groups received a cholesterol-enriched diet for six weeks. Group C. oblongaleaf as drinking supplement well. After weeks, normal substituted groups another (control group) maintained throughout regular diet. At end 12th week, left testes animals resected light microscopic with particular attention maturity germ cells seminiferous tubules using Johnsen's score. Increase intertubular connective tissue diameter vessels, abundant spermatogonia primary spermatocytes along reduced germinal epithelium noted all 1. The remaining had no significant changes their sections. mean score (4.20±1.92) significantly lower than that (7.33±0.52) (7.05±0.07). (P=0.01). Inconclusion, (C. protected rabbit from damage hypercholesterolemia.