Successful Treatment of Cerebral Tuberculoma in Acquired Immune Deficiency Syndrome Patient a Case Report

• DOI: 10.47191/ijmscrs/v4-i04-08
• Publication Date: 2024-04-10T06:50:32Z
• Authors: Rachmad Aji Saksana; Ika Trisnawati; ; Eko Budiono
• Keywords: Tuberculoma; GeneXpert MTB/RIF

Introduction: Tuberculosis (TB) remains a leading problem in developing and endemic countries. Cerebral tuberculosis is rare but dangerous complication of infection the central nervous system. The immunosuppressive condition human immunodeficiency virus risk factor for severe tuberculosis. Case Report: An Indonesian man, 32 years old, married, came with complaints headaches, dizziness, delirium, nausea vomiting since 1 month before examination. He had history TB treatment year results neurological examination were within normal limits, HIV test was reactive there decrease CD4. Head MRI contrast showed multiple solid nodules thalamus largest size 2.3×2.7 cm, indicating cerebral tuberculoma. Chest x-ray normal, GeneXpert MTB sputum not detected. Next, primary given anti-tuberculosis drugs, Highly Active Antiretroviral Therapy (HAART), co-trimoxazole, dexamethasone. There clinical, laboratory radiological improvement after 12 months treatment. Viral load undetectable, CD4 elevated. A head CT scan did show became healthy able to return work Discussion: tuberculoma characterized by presence intracranial clinical manifestations are non-specific, such as headaches or seizures. This caused space occupying lesions increase pressure. In this case, diagnosis made through contrast. therapy co-trimoxazole soon made, while antiretrovirals 2 weeks he has tolerated medication. minimum duration months. require lifelong antiretroviral Conclusion: Tuberculoma should be considered differential space-occupying patients HIV/AIDS. Early diagnosis, adequate therapy, patient adherence family support can cure