Outpatient use of tPA to recanalize thrombosed native fistulas a case series and discussion of literature

• DOI: 10.47482/acmr.2022.56
• Publication Date: 2022-06-13T13:26:32Z
• Authors: Işıl Yıldız; Can Çalışkan; Demet Gündüz
• Keywords: Interventional radiology

Background: The present study aims to evaluate the effectiveness of ultrasound-guided percutaneous alteplase (t-PA) injection for treatment long segment ( ≥14cm) thrombi in efferent veins native arteriovenous fistulas hemodialysis patients. Methods: A total 9 patients who underwent t-PA application under ultrasound guidance interventional radiology clinic between 2019 and 2021 were included study. During intervention, information such as thrombosed length, dose, number sessions, presence aneurysmal segment, bleeding after intervention need transluminal angioplasty (PTA) recorded. Restoring flow fistula was considered successful outcome. All statistical evaluations performed with IBM SPSS Statistics 21 software (version 21.0; Inc, Chicago, Illinois) Windows. Results: Mean age 48.7±14 years, 28.7±11 months, thrombosis 3.5±2 days, length 17.7±2.9 cm. Post-intervention that did not require encountered 2 patients, stenosis proximal 6 PTA applied 7 t-PA. After interventions, effective provided all Conclusion: Ultrasound-guided should be an which is less invasive, can outpatient has fewer complications, even if segments are (>10 cm). This technique avoids potential endothelial damage saves cost mechanical devices.