Predictive value of drain fluid amylase level on postoperative day one after pancreatic resection for predicting postoperative pancreatic fistula

• DOI: 10.47717/turkjsurg.2024.6292
• Publication Date: 2024-03-30T09:12:23Z
• Authors: Ahmet Çağrı Büyük...; Kürşat Dikmen; Aydın Yavuz; Saygın Altıner; Hüseyin Göbüt; Ahmet Cihangir Emral; Hasan Bostancı; Mustafa Kerem
• Keywords: Pancreatic fistula

Objective: The aim of this study was to evaluate the predictive value first postoperative day (POD1) drain fluid amylase in predicting pancreatic fistula formation following pancreaticoduodenectomy (PD). Material and Methods: One-hundred eighty-five prospective patients undergoing PD between April 2014 2018 were studied retrospectively. Cut-off point predict development POPF determined by median values for 1883 U/L. Patients classified into two groups according POD1 values: <1883 U/L (Group 1) ≥1883 2). Differences with clinically relevant without evaluated. Results: incidence 17.2%. level strongest predictor POPF, levels higher than demonstrating best accuracy (87.5%), sensitivity (78.1%), specificity (89.5%), positive (60.9%), negative (95.1%). forty-four (77.8%) had a less U/L, developed only seven (3.7%) cases, whereas or (n= 41), rate 31.4% [OR: 22.24, 95% CI (7.930–62.396), p<0.001]. Conclusion: cut-off (1883 U/L) might adequate rates resection.