Correlation of adipokines with obesity indices and lipid profile inchronic kidney disease

• DOI: 10.51248/.v40i2.64
• Publication Date: 2020-11-11
• Authors: Ganesh Bhandari; AR Shivashankara; J Manjunath
• Keywords: Resistin; Dyslipidemia; Lipid Profile

Introduction and Aim:Adipokines are proposedto be involved in the pathogenesis of chronic kidney disease (CKD) its association with cardiovascular disease. In present study, we aimed to assess levels adiponectin resistin CKD patients find correlation these adipokines obesity indices, serum lipid profile, progression. Materials Methods:Twenty-six each stages 2 3 (Group-I), 4 5 (Group-II) healthy controls (Group-III) were subjects this study. studysubjects, body mass index (BMI), waist hip ratio (W/H), triglycerides, total cholesterol, LDL HDL adiponectin, measured. Results:We observed a significant increase resistin, decrease cholesterol when compared (P <0.001). There was negative patients. Serum level differed significantly between groups I II, indicating positive progression CKD. Conclusion:The study revealed dyslipidemia altered adipokinesin CKD. Findings profile could have implications utilizing as diagnostic prognostic biomarker Future studies larger sample size, including all assessing risk factors required. Keywords:Adiponectin; disease; profile; obesity; resistin.