Study on Antioxidant and Antimicrobial Efficacy of Cyphostemma setosum (Roxb.) Alston,Leaves: Implications for Natural Therapeutics

• DOI: 10.51470/psa.2024.9.4.11
• Publication Date: 2025-01-09T10:17:43Z
• Authors: P. Vijay Kumar; G. Prabhakar; ; P. Kamalakar

Plants undergo significant abiotic and biotic stresses, resulting in heightened formation of reactive oxygen species (ROS) that can oxidize cellular components disrupt physiological functioning. In response, plants have evolved intricate antioxidant systems, comprising enzymes non-enzymatic substances, to neutralize avert oxidative damage. This research assessed the antioxidant, antibacterial, antifungal properties C. setosum leaf extracts. Cyphostemma (Roxb.) is a succulent climber clothed with scattered grandular bristly hairs; it belonging family Vitaceae. The activity was evaluated by DPPH phosphomolybdenum tests. experiment, Vitamin C exhibited maximum (98%) at 80 µg/ml, succeeded methanol (92%), chloroform (82%), petroleum ether extracts (72%), while ethyl acetate extract displayed lowest (48%). experiment indicated Gallic Acid Ascorbic serve as standards elevated total capacities (TACs) 92% 85%, respectively. highest capacity (TAC) among plant 82%, followed 73%, 62%, 59%, underscoring significance solvent polarity extraction. demonstrated antibacterial against Pseudomonas fluorescens, E. coli, Staphylococcus aureus, Bacillus subtilis, exhibiting inhibition zones 8-9 mm, (6-7 mm), (5-7 (3-6 mm). Ampicillin enhanced efficacy, ranging from 8 15 mm. Correspondingly, efficacy F. oxysporum, S. rolfsii, P. infestans most potent, rates 60%, 52%, Chloroform, acetate, moderate but fungicide Fluconazole 50-55%. findings highlight potential substantial source natural antioxidants, agents, positioning prospective candidate for health functional food applications.