Predictive factors for malignancy in undiagnosed isolated small bowel strictures

• DOI: 10.5217/ir.2017.15.4.518
• Publication Date: 2017-11-13T04:38:09Z
• Authors: Ujjwal Sonika; Sujeet Saha; Saurabh Kedia; Nihar Ranjan Dash; Sujoy Pal; Prasenjit Das; Vineet Ahuja; Peush Sahni
• Keywords: Etiology; Medical record; Univariate analysis

Patients with small bowel strictures have varied etiologies, including malignancy. Little data are available on the demographic profiles and etiologies of in patients who undergo surgery because intestinal obstruction but do not a definitive pre-operative diagnosis.Retrospective were analyzed for all operated between January 2000 October 2014 without mass lesions definite diagnosis after imaging endoscopic examinations. Demographic parameters, imaging, endoscopic, histological extracted from medical records. Univariate multivariate analyses conducted to identify factors that could differentiate tuberculosis (ITB) Crohn's disease (CD) malignant benign strictures.Of 7,425 reviewed records, 89 met inclusion criteria. The most common site was proximal intestine (41.5%). diagnoses ITB (26.9%), CD (23.5%), non-specific (20.2%), malignancy (15.5%), ischemia (10.1%), other complications (3.4%). older than (47.6±15.9 years vs. 37.4±16.4 years, P=0.03) age >50 had specificity etiology 80%. Only 7.1% more 1 stricture 64% proximally located strictures. Diarrhea only factor predicted 6.5 (95% confidence interval, 1.10-38.25; P=0.038) compared ITB.Malignancy cause approximately 16% patients, especially among single location. Empirical therapy should be avoided threshold surgical resection is low these patients.