Spectrum of microbiota in diabetic foot infections in a teaching hospital of Uttar Pradesh

• DOI: 10.5455/ijmsph.2018.0617809062018
• Publication Date: 2018-06-21T22:12:47Z
• Authors: Sweta Singh; Gopa Banerjee; Jyotsna Agarwal; Vijay Kumar; Kauser Usman
• Keywords: Uttar pradesh; Foot (prosody); Broad spectrum

Background: Diabetic foot ulcer is the leading cause of non-traumatic lower extremity amputations. A prospective case–control study was carried out on 50 patients with diabetic ulcers (cases) and non-diabetic (controls) to determine microbiological profile, their antibiotic sensitivity patterns along different demographic parameters. The prevalence extended-spectrum beta-lactamases (ESBLs) producers, carbapenemase methicillin-resistant Staphylococcus aureus among isolates potential risk factors for infection these multidrug-resistant organisms (MDROs) also studied outcome infections.

Objectives: present aims at identifying spectrum in infections pattern a developing country, like India.

Materials Methods: Clinical specimens were taken from each patient ulcers. These processed culture (aerobic anaerobic), further identification testing. ESBL production detected by phenotypic methods automated VITEK-2 system, results mutually compared two methods.

Results: total 158 (155 bacteria 3 fungi) isolated giving an average organisms/patient. Cases mostly positive polymicrobial growth (77%) as controls, tissue most yielding sample. Gram-negative aerobes predominantly isolated, followed Gram-positive aerobes. Anaerobic (3%) fungal seen case samples.

Conclusion: Escherichia coli (33%) S. (7%) organisms, while Candida fungus. strong association peripheral vascular disease (PVD), smoking (P = 0.001), well neuropathy 5 cm2, osteomyelitis