Echinococcus granulosus comparative genotyping in sheep in Saudi Arabia and Egypt

• DOI: 10.5455/ovj.2024.v14.i3.14
• Publication Date: 2024-04-13T16:27:16Z
• Authors: Abdulsalam Alkhaldi
• Keywords: Echinococcus

Background: Cystic echinococcosis, which is triggered by the parasite Echinococcus granulosus, a global zoonotic disease that common in rural regions there are frequent encounters between dogs and other domestic animals. The can have devastating consequences, impacting health of people animals leading to huge financial losses, especially agricultural industry. In Kingdom Saudi Arabia (KSA) Egypt, despite high incidence disease, few investigations been conducted into genetic variation species genus Echinococcus. Aim: This study sought compare features hydatid cysts carried sheep KSA with those found Egypt. Methods: DNA from protoscolices was used PCR targeting mitochondrial NADH dehydrogenase 1 (NAD1), cytochrome c oxidase subunit (COX1), nuclear actin II (ACT II) genes, resulting amplification products 30 Egyptian isolates were sequenced compared. Results: Among KSA, overall prevalence cystic echinococcosis 0.51%. Of cyst samples, 95%, 100%, 52% positive for Cox1, nad1, act respectively. Targeting all three samples belonged E. granulosus genotype (G1), whereas (G1) canadensis (G6). Conclusions: We conclude two countries shared origin Arabic North Africa, camels as hosts.