Evaluation of Antioxidant and Free Radical Scavenging Activity of Samadera indica Using In vitro Models

• DOI: 10.5530/pj.2011.23.13
• Publication Date: 2011-07-26T17:57:13Z
• Authors: Vidya Viswanad; N.A. Aleykutty; Subin Mary Zacharia; Litha Thomas
• Keywords: ABTS; Scavenging

Antioxidant has gained importance in the current scenario as it an ability to trap free radicals which are produced during degenerative diseases. Natural antioxidant is considered superior synthetic safe and produces a prominent action. Samadera indica bitter plant widely distributed throughout India, mostly found evergreen forest of Western Ghats along river shore, bitterness due presence flavanoids like Quassinoids. Literatures showed Quassinoids therefore, may show activity not yet ruled out. Hence present study was focused out evaluate by in-vitro models. Method: The leaf extracted using methanol acetone solvent. extracts were evaluated for radical scavenging assay DPPH, ABTS assay, FRAP, DCF/AAPH expressed IC50. Result: All methods but comparatively lower than standard Quercetin. increased dose dependent manner. Conclusion: evaluation concludes that this be flavanoids. Hence, further work should done on isolation identification other components indica.