Calotropin: Natural Phytomolecules for Cutting-edge Features

• DOI: 10.5530/pres.16.1.3
• Publication Date: 2023-12-14T10:03:24Z
• Authors: Sourav Nag; Reshmi Paul; Sumanta Mondal; Naresh Panigrahi; Partha Roy

Pharmacognosy Research,2023,16,1,19-25.DOI:10.5530/pres.16.1.3Published:December 2023Type:Review ArticleAuthors:Sourav Nag, Reshmi Paul, Sumanta Mondal, Naresh Panigrahi, and Partha Roy Author(s) affiliations:Sourav Mondal*, Department of Pharmaceutical Chemistry, School Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, INDIA. Abstract:Phytochemical is a collective term for plant chemicals with varied structure function. The most common sources phytochemicals are fruits, vegetables, whole grains, nuts seeds, other foods. Calotropin pharmacologically active compound isolated from milkweed plants like Calotropis procera, gigantea, Asclepias curassavica that belong the Asclepiadaceae family which used medicinal purposes in many Asian countries. identified as highly potent cardenolide has similar chemical cardiac glycosides (such digoxin digitoxin). Among cardenolides, calotropin promising agent. cytotoxic anti-tumor impacts, cancers breast, colon, lung, leukemia malignancies exhibiting significant effects. effects on cancer have been extensively studied preclinical pharmacological studies vitro using cell lines vivo experimental animal models targeted antitumor mechanisms anticancer signaling pathways. During ancient times, was utilized various techniques. A macerated bark extract frequently de-hearing hides tanning. particularly effective abortifacient or interceptive agent females. Cardenolide poisonous. This critique focused its chemistry therapeutic activity cells. Keywords:Asclepias curassavica, Calotropin, Cardenolide.View:PDF (595.4 KB)