Diagnosis of Churg-Strauss Syndrome Presented With Neuroendocrine Carcinoma: A Case Report

• DOI: 10.5535/arm.2017.41.3.493
• Publication Date: 2017-07-27T02:43:01Z
• Authors: Dayun Park; Ho Jun Lee; Kwang Hoon Lee; Bum Sun Kwon; Jin-Woo Park; Ki Yeun Nam; Kyoung Hwan Lee
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Case Report; 3. Good health

Churg-Strauss syndrome (CSS) is a rare systemic vasculitis that affect small and medium-sized blood vessels and is accompanied by asthma, eosinophilia, and peripheral neuropathy. This report describes a case of a 52-year-old man who had a history of sinusitis, asthma, and thymus cancer and who had complained of bilateral lower extremity paresthesia and weakness for a month. Peripheral neuropathy was detected by electrodiagnostic studies. Resection of a mediastinal mass, which was diagnosed as thymic neuroendocrine carcinoma, was performed five months before his visit. After thymectomy, peripheral blood tests revealed a gradual increase in eosinophils. Two months after surgery, he was admitted to the hospital for dyspnea, and nodules of focal consolidation were found in his chest X-ray. One month later, pyoderma occurred in the right shin, and the skin biopsy showed extravascular eosinophilic infiltration. He was diagnosed with CSS after thymectomy, and we report a very rare case of CSS presented with thymic neuroendocrine carcinoma.