Prognostic Significance of The New Criteria for Acute Kidney Injury in Cirrhosis

• DOI: 10.5604/01.3001.0011.7390
• Publication Date: 2018-05-09T10:25:00Z
• Authors: Emilia T.O. Bansho; Pedro Eduardo S. ...; Bruno S. Colombo; Leticia M. Wildner; Maria Luiza Bazzo; Esther B. Dantas-...; Leonardo L. Schiavon; Janaína L. Narcis...
• Keywords: Decompensation; Clinical Significance

Introduction and aim. New criteria for acute kidney injury (AKI) in cirrhosis have been proposed, but its prognostic significance is unclear. This study aims to evaluate the of AKI cirrhotic patients hospitalized decompensation. Material methods. a prospective cohort study. was defined as an increase creatinine (Cr) levels ≥ 0.3 mg/dL 48 h or 50% basal value last 7d. divided into stages 1 (elevation: < 2x basal), 2 (2 3x), 3 (> 3x). Results. In this study, 227 aged 53.9 ± 11.5 years were included, whom 37% had (28% AKI1, 5% AKI2, 4% AKI3). Thirty percent died transplanted within 90 days from causes related presence ascites at hospital admission higher values Chronic Liver Failure-Sequential Organ Failure Assessment (CLIF-SOFA) scores, not AKI. regression analysis conducted assess effect final Cr level with AKI, 90-day mortality associated ascites, CLIF-SOFA score, 1.5 mg/dL. The showed lower transplant-free survival rates than those without AKI1 Conclusions. Early frequent transplantation only when Distinct approaches are needed according Cr.