Searching for a Marker of REM Sleep Behavior Disorder: Submentalis Muscle EMG Amplitude Analysis during Sleep in Patients with Narcolepsy/Cataplexy

• DOI: 10.5665/sleep/31.10.1409
• Publication Date: 2017-09-07T06:45:41Z
• Authors: Raffaele Ferri; Christian Frances...; Marco Zucconi; Stefano Vandi; Francesca Poli; Oliviero Bruni; Carlo Cipolli; Pasquale Montagna; Giuseppe Plazzi
• Keywords: Sleep; Sleep Stages

To evaluate the amplitude of submentalis muscle EMG activity during sleep in patients with narcolepsy/cataplexy or without REM behavior disorder (RBD). Observational study consecutive recruitment. Sleep laboratory. Thirty-four and 35 age-matched normal controls. Half (17 subjects) had a clinical video polysomnographic diagnosis RBD. The average rectified signal was used to assess atonia, new Atonia Index computed. Chin activations were detected their duration interval analyzed. lower both patient groups (with narcolepsy RBD showing lowest values) respect controls, it did not correlate age as total number chin significantly higher than No significant differences found between two patients, although more noted those without. Elevated is only marker This shows that polysomnographically evident present many narcolepsy/ cataplexy. condition might be specific narcolepsy/cataplexy, reflecting peculiar form related motor dyscontrol (i.e., status dissociatus), paving way enacting dream behaviors, correlated neurochemical neuropathological substrate narcolepsy/cataplexy.