Prostate‐specific antigen levels in men aged 70 years and over: findings from the CHAMP study

• DOI: 10.5694/j.1326-5377.2012.tb04214.x
• Publication Date: 2019-09-24T09:06:47Z
• Authors: Melisa J Litchfield; Robert G Cumming; David P Smith; Vasi Naganathan; David G Le Couteur; Louise M Waite; Fiona M Blyth; David J Handelsman
• Keywords: Rectal examination; Prostate cancer screening

Objective: To describe values of serum prostate-specific antigen (PSA) in older men without diagnosed prostate cancer, categorised by age and country birth, to self-reported cancer screening. Design, participants setting: A cohort study (the Concord Health Ageing Men Project) involving a representative sample 1434 eligible community-dwelling with no diagnosis who were aged 70 years over living defined geographic area Sydney, baseline data collected between 28 January 2005 4 June 2007. Main outcome measures: Serum PSA levels Results: 11% (155) had level ≥ 6.5 ng/mL, increasing from 7.5% 70–74 31.4% 90 years. varied ethnicity, Australian-born (695) having the highest (median, 2.3 ng/mL; 5th–95th percentile, 0.4–10.1 ng/mL), followed born China (n = 42; 2.1 0.4–12.4 United Kingdom Ireland 70; 1.9 0.3–8.9 Greece 59; 1.5 0.2–6.1 Italy 293; 1.4 0.3–7.2 ng/mL). test previous 2 was reported 48% participants, digital rectal examination (DRE) 37%. Conclusions: significant number recent tests. The ranges this will help interpreting findings