Effects of low-purine diet supplemented with Sida acuta Burm. f. on growth performance, purine deposition, and biomolecules in slow-growing chickens

• DOI: 10.5713/ab.24.0798
• Publication Date: 2025-02-27T05:06:06Z
• Authors: Orapin Jantasaeng; Michel Jacques Du...; Kanjana Thumanu; Supattra Okrathok; Sutisa Khempaka

This study investigated the effects of a low-purine (Pu) diet supplemented with Sida acuta Burm. f. (SA) on growth performance, serum uric acid (SUA), and meat quality, including chemical composition, biomolecules, purine deposition, in slow-growing Korat chickens (KRC). A total 480 mixed-sex one-d-old KRC were randomly allocated into five groups six replicates each (16 chicks/replicate) using 1+2×2 augmented factorial experiment completely randomized design. Five experimental diets as follows: control (basal diet), two 30 45% lower levels than (-30 -45% Pu), SA (0.3 0.6% SA), respectively. After sex determination, all subsequent analyses conducted exclusively female birds. fed -30% Pu showed reduced hypoxanthine deposition major breast muscle (Pectoralis major) without negative SUA levels, protein secondary structures comparable to group. Birds diet, either 0.3 or SA, exhibited impaired performance significant changes content. Correlation analysis revealed that was positively correlated content, while showing correlations lipid content ß-turn structure. 30% reduction dietary purines combined supplementation effectively decreased chicken meat, contributing production healthier product. Further studies are needed investigate molecular mechanisms metabolic pathways, which will enable breeders advance development production.