Pregnancy and Embryonic Loss Among Timed Artificial Insemination Protocols in Post-partum Dairy Buffaloes (Bubalus bubalis)
Bubalus
Swamp
Identification
Water buffalo
DOI:
10.6000/1927-520x.2025.14.02
Publication Date:
2025-01-24T15:40:48Z
AUTHORS (4)
ABSTRACT
Background: Albinism is a genetic condition marked by lack of melanin in the skin, hair, and eyes, leading to increased sensitivity light susceptibility skin cancer. Oculocutaneous albinism buffaloes caused G>A mutation tyrosinase gene, which introduces premature stop codon, rendering enzyme inactive. Despite efforts prevent defects, persists because it an autosomal recessive trait. This study used capillary sequencing analyze gene local buffaloes. Methods: One hundred forty-eight (148) were sampled for genomic DNA extraction, followed PCR amplification reported region with associated albinism. The products subjected Sanger chain termination sequencing. Genotypic frequencies computed manually, phenotypic association was done descriptively. Results: proportion phenotypically albino-looking 4.76% animals are homozygous A allele at position 1494 gene. These all riverine-type Phenotypically white but pigmented irises swamp comprised 4.17% animals. All sampled, including irises, G 1494, suggesting these not similar cases oculocutaneous Conclusions: established baseline data on prevalence identified new mutations further research their effects color phenotypes production potential.
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