Central Nervous System Cancers

• DOI: 10.6004/jnccn.2011.0036
• Publication Date: 2017-04-14T15:59:34Z
• Authors: Steven S. Brem; Philip J. Bierman; Henry Brem; Nicholas Butowski; Marc C. Chamberlain; Ennio A. Chiocca; Lisa M. DeAngelis; Robert A. Fenster...; Allan Friedman; Mark R. Gilbert; Deneen Hesser; Larry Junck; Gerald P. Linette; Jay S. Loeffler; Moshe H. Maor; Madison Michael; Paul L. Moots; Tara Morrison; Maciej Mrugala; Louis Burt Nabors; Herbert B. Newton; Jana Portnow; Jeffrey J. Raizer; Lawrence Recht; Dennis C. Shrieve; Allen K. Sills; Frank D. Vrionis; Patrick Y. Wen
• Keywords: Central Nervous System Neoplasms; 03 medical and health sciences; 0302 clinical medicine; Humans

In 2010, an estimated 22,020 new cases of primary brain and other nervous system neoplasms were diagnosed in the United States, 1 approximately 13,140 deaths occurred from these tumors.The incidence malignant tumors has been increasing over past 30 years, especially elderly persons. 2 Metastatic disease to central (CNS) occurs much more frequently, with 10 times that tumors.Between 20% 40% patients systemic cancer will develop metastases.