Role of a Risk of Malignancy Index in Clinical Approaches to Adnexal Masses

• DOI: 10.7314/apjcp.2014.15.18.7793
• Publication Date: 2014-12-01T01:43:29Z
• Authors: Hakki Sencer Simsek; Aytekin Tokmak; Emre Ozgu; Melike Doganay; Nuri Danisman; Salim Erkaya; Tayfun Gungor
• Keywords: Adnexal mass

The aim of this study was to evaluate predictive role risk malignancy index in discriminating between benign and malignant adnexal masses preoperatively.This retrospective conducted with a total 569 patients masses/ovarian cysts managed surgically at our clinic January 2006 2012. Obtained data from patient files were age, gravidity, parity, menopause status, ultrasound findings CA125 levels. For all scans performed. the assessment (RMI) Jacobs' model used. Histopathologic results recorded postoperatively. Malignancy status removed mass gold standard.Of masses, 245 (43.1%) malignant, 316 (55.5%) 8 (1.4%) borderline. mean age cases lower than malign (35.2±10.9 versus 50.8±13.4, p<0.001). Four hundred five them (71.2%) premenopausal period. Malignant tumors more frequent postmenopausal women (81% 29%, All parameters RMI statistically significantly favorable for masses. In ROC curve analysis provided maximum Youden level 163.85. When we based on cutoff as 163.85 sensitivity, specificity , PPV, NPV calculated 74.7%, 96.2%, 94% 82.6%, respectively.RMI found be significant marker preoperative evaluation management an mass, useful referring tertiary care centers. Although utilization provides increased diagnostic accuracy new tools higher sensitivity are needed discriminate ovarian cancer