Glioma Epidemiology in the Central Tunisian Population: 1993-2012

• DOI: 10.7314/apjcp.2014.15.20.8753
• Publication Date: 2014-12-29T21:49:18Z
• Authors: Saoussen Trabelsi; Dorra H'mida-Ben ...; Mohamed Ladib; Nadia Mama; Imed Harrabi; Kalthoum Tlili; Mohamed Tahar Yac...; Hedi Krifa; Sihem Hmissa; Ali Saad; Moncef Mokni
• Keywords: Adult; Aged, 80 and over; Male; Chi-Square Distribution; Adolescent; Brain Neoplasms; Glioma; Kaplan-Meier Estimate; Middle Aged; Prognosis; Disease-Free Survival; 3. Good health; 03 medical and health sciences; Age Distribution; 0302 clinical medicine; Prevalence; Humans; Female; Registries; Sex Distribution; Developing Countries; Aged; Retrospective Studies

Background: Glioma is a heterogeneous central nervous system (CNS) tumor group that encompasses different histological subtypes with high variability in prognosis. The lesions account for almost 80% of primary malignant brain tumors. aim this study to extend our understanding the glioma epidemiology Tunisian region. Materials and Methods: We analyzed 393 gliomas recorded cancer registry Tunisia from 1993 2012. Crude incidence rates (CR) world age-standardized (ASR) were estimated using annual population data size age structure. Statistic correlations established Chi-square Kaplan-Meier test. Results: patients identified mean at diagnosis 48 years 1.5 sex ratio (male/female). During 19 period highest value was observed male between 1998 2002 (CR: 0.28, ASR: 0.3). Incidence results underline increasing grade occurring adulthood last (2007-2012). Median survival 27 months, 1-, 2- 5-year 42%, 30% 26%, respectively. Survival greater younger age, lower grade, infratentrial location undergoing palliative treatment. Conclusions: This provides important information could improve management healthcare practice.