Multicenter Epidemiologic Study on Hepatocellular Carcinoma in Turkey

• DOI: 10.7314/apjcp.2014.15.6.2923
• Publication Date: 2014-07-10T07:44:48Z
• Authors: Alper Can; Erkan Dogan; Ibrahim Vedat Bay...; Ali Murat Tatli; Mehmet Besiroglu; Murat Kocer; Ahmet Cumhur Dulger; Ummugul Uyeturk; Derya Kivrak; Zuat Orakci; Oznur Bal; Turgut Kacan; Sehmus Olmez; Nedim Turan; Mehmet Fatih Ozbay; Ahmet Alacacioglu
• Keywords: Hepatitis B; Etiology; Alcohol abuse; Viral Hepatitis; Liver Cancer; Hepatitis C; Turkish population

Background: Hepatocellular cancer (HCC) is one of the important health problems in Turkey, being very common and highly lethal. The aim this study was to determine clinical, demographic features risk factors. Materials Methods: Nine hundred sixth-three patients with HCC from 13 cities Turkey were included study. Results: Only 205 (21%) 963 women, a male:female predominance 4.8:1 median age 61 years. etiologic factors for hepatitis B 555 (57.6%), 453 (81%) men, 102 (19%) again male predominance, C 159 (16.5%), (14.9% 22.4%, higher incidence women), chronic alcohol abuse (more than ten years) 137 (14.2%) (16.8% 4.9%, males). Child-Pugh score paralleled advanced disease stage amd also high level AFP. Conclusions: According our findings viral etiology (hepatitis infections) Turkish population most factor development, as third factor. classification AFP levels determined be prognostic patients.