Analysis on Early Detection of Lung Cancer by PET/CT Scan

• DOI: 10.7314/apjcp.2015.16.6.2215
• Publication Date: 2015-10-14T02:18:02Z
• Authors: Huo-Qiang Wang; Long Zhao; Juan Zhao; Qiang Wang
• Keywords: Lung Neoplasms; Prognosis; Multimodal Imaging; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Meta-Analysis as Topic; Fluorodeoxyglucose F18; Positron-Emission Tomography; Humans; Tissue Distribution; Radiopharmaceuticals; Tomography, X-Ray Computed; Early Detection of Cancer; Neoplasm Staging

This systemic analysis was conducted to to evaluate the application value of positron emission tomography/computed tomography (PET/CT) in early diagnosis of lung cancer.Clinical studies evaluating the application value of PET/CT for patients underwent PET/CT imaging. The histological diagnosis served as the standard of truth.Four clinical studies which including 1330 patients with pulmonary space- occupying lesions were considered eligible for inclusion. Systemic analysis suggested that, in all 1330 patients, pooled sensitivity was 98.7% (1313.2/1330) and specificity was 58.2%(276.85/476).This systemic analysis suggests that integrated PET/CT imaging provides high sensitivity, and reasonably high specificity, and could be applied for early diagnosis of lung cancer.