Retention in care outcomes for HIV pre‐exposure prophylaxis implementation programmes among men who have sex with men in three US cities

• DOI: 10.7448/ias.19.1.20903
• Publication Date: 2016-06-13T06:26:11Z
• Authors: Philip A Chan; Leandro Mena; Rupa Patel; Catherine E Olden...; Laura Beauchamps; Amaya G Perez‐Brumer; Sharon Parker; Kenneth H Mayer; Matthew J Mimiaga; Amy Nunn
• Keywords: Pre-exposure prophylaxis; Male Homosexuality

Introduction Despite the efficacy of pre‐exposure prophylaxis (PrEP) in preventing HIV transmission, few studies have evaluated PrEP use and retention care outcomes real‐world settings outside clinical trials. Methods Data were collected from programmes three mid‐size US cities: Providence, Rhode Island (RI); Jackson, Mississippi (MS); St. Louis, Missouri (MO). We assessed demographic social characteristics patients prescribed documented their insurance copayment experiences. at six months. Multivariate analyses used to predict among men who sex with (MSM). acquisition cohort was also assessed. Results A total 267 (RI: 117; MS: 88; MO: 62) PrEP; 81% filled prescriptions 73%; 82%; 94%; p <0.001). Patients MS MO more commonly African American than RI (72% 26% vs. 7%, respectively), but less frequently Latino (2% 3% 24%, respectively). More reported living below federal poverty line (52%) compared (23%) (26%). Most MSM 92%; 88%; 84%). The majority recent condomless anal 70%; 65%; 75%). Among 171 least months beforehand, 72% retained 68%; 87%; =0.12) 57% 53%: 61%; 63%; =0.51). Insurance status medication costs not found be significant barriers for obtaining PrEP. Three became infected during six‐month period after being (1.1%; 3/267), including one (suspected acute infection), (confirmed poor adherence) (seroconverted just prior initiation). Conclusions initiation differed across these distinct settings. In contrast, consistently suboptimal sites. Further research is needed identify individual, structural factors that may impede or enhance