Auxin-regulated chromatin switch directs acquisition of flower primordium founder fate

• DOI: 10.7554/elife.09269
• Publication Date: 2015-10-13T00:29:47Z
• Authors: Miin-Feng Wu; Nobutoshi Yamaguchi; Jun Xiao; Bastiaan Bargmann; Mark Estelle; Yi Sang; Doris Wagner
• Keywords: Primordium; Reprogramming; SWI/SNF; Cell fate determination; SMARCA4

Reprogramming of cell identities during development frequently requires changes in the chromatin state that need to be restricted correct populations. Here we identify an auxin hormone-regulated switch directs reprogramming from transit amplifying primordium founder fate Arabidopsis inflorescences. Upon sensing, MONOPTEROS transcription factor recruits SWI/SNF remodeling ATPases increase accessibility DNA for induction key regulators flower initiation. In absence hormonal cue, sensitive Aux/IAA proteins bound block recruitment addition recruiting a co-repressor/histone deacetylase complex. This simple and elegant hormone-mediated is ideally suited iterative initiation orchestrates additional auxin-regulated transitions. Our findings establish new paradigm nuclear response auxin. They also provide explanation how this small molecule can direct diverse plant responses.