DunedinPACE, a DNA methylation biomarker of the pace of aging

• DOI: 10.7554/elife.73420
• Publication Date: 2022-01-14T13:00:40Z
• Authors: Daniel W Belsky; Avshalom Caspi; David L Corcoran; Karen Sugden; Richie Poulton; Louise Arseneault; Andrea Baccarelli; Kartik Chamarti; Xu Gao; Eilis Hannon; Hona Lee Harrington; Renate Houts; Meeraj Kothari; Dayoon Kwon; Jonathan Mill; Joel Schwartz; Pantel Vokonas; Cuicui Wang; Benjamin S Williams; Terrie E Moffitt
• Keywords: Epigenome; Pace

Measures to quantify changes in the pace of biological aging response intervention are needed evaluate geroprotective interventions for humans. Previously, we showed that quantification from a DNA-methylation blood test was possible (Belsky et al., 2020). Here, report next-generation biomarker Pace Aging, DunedinPACE (for Aging Calculated Epigenome).