Correlation of Urine Protein/Creatinine Ratio in Late Pregnancy with Pregnancy Outcome in Patients with Preeclampsia Combined with Hyponatremia

• DOI: 10.7754/clin.lab.2024.240723
• Publication Date: 2025-02-19T09:02:58Z
• Authors: Ping Zhu; Jian Wei; Xiao Liu; Ren Huang; Ping Liu; Min Zeng; Jun Li

This study aimed to analyze the correlation of urine protein/creatinine ratio (UPCR) in late pregnancy with outcomes patients preeclampsia (PE) combined hyponatremia. The data 288 PE were collected and compiled for retrospective analysis. divided into two groups: observation group (52 cases, complicated hyponatremia) control (236 not hyponatremia). general conditions, clinical data, adverse maternal infant statistically analyzed both groups. Risk factors using logistic regression, predictive efficacy was assessed ROC curves. Comparing groups, differences significant (all p > 0.05). Multifactorial analysis showed that uric acid (OR = 0.001, 0.010) 24-hour urinary protein 2.654, 0.001) independent risk hyponatremia PE. In group, placental abruption (9.6%, 0.015), hepatic renal impairment (38.6%, < 0.001), pleural effusion (30.7%, fetal growth restriction (50.0%, fundus lesions (7.6%, 0.012), HELLP syndrome (7.7%, 0.017), mild neonatal asphyxia (17.3%, 0.025), severe (3.8%, 0.046), metabolic acidosis intrauterine infection (5.7%, 0.004), hospitalization exceeding 20 days occurred a higher percentage than group. There no difference postpartum hemorrhage, eclampsia, respiratory distress syndrome, abortion, or death UPCR is an factor Patients are at high outcomes.