Antimicrobial Resistance Patterns of Common Gram-Negative Microorganisms Isolated from Patients with Lower Respiratory Tract Infections in a Teaching Hospital in Vietnam

• DOI: 10.7883/yoken.jjid.2023.260
• Publication Date: 2024-01-30T22:12:28Z
• Authors: Hoang Huy Le; An Van Nguyen; Luong Huy Vu; Vinh Thi Ha Nguyen; Hoa Quynh Pham; Hung Van Le; Son Thai Nguyen; Hong Thu Le; Hung Viet Dinh; Nam Van Le; Tuan Dinh Le; Minh Nhat Le; Viet Hoang Nguyen; Kien Trung Hoang; Hai Ha Long Le
• Keywords: Gram; Respiratory tract; Gram-Negative Bacteria

This cross-sectional study investigated the antimicrobial resistance (AMR) patterns of gram-negative pathogens isolated from 4,789 hospitalized patients with lower respiratory tract infections (LRTIs). Of collected specimens, 1,325 (27.7%) tested positive for bacteria. Acinetobacter baumannii (38.6%), Pseudomonas aeruginosa (33.5%), Klebsiella pneumoniae (18.7%), Escherichia coli (5.6%), and aerogenes (3.5%) were most prevalent isolates. AMR analysis revealed high rates (79.9%-100%) A. isolates to multiple classes antibiotics except amikacin, trimethoprim/sulfamethoxazole, colistin. P. displayed low colistin (< 10%) but other antibiotics. K. 90.0%-100.0% penicillins, whereas notably (7.1%) amikacin (16.7%). exhibited various sensitivity (95.1%), ampicillin (100.0%), (100.0%). E. (96.9%) maximum several Our identified significant trends highlighted prevalence multidrug-resistant strains (93.6% 69.1%-92.4% isolates). These findings emphasize urgent need appropriate antibiotic management practices combat in associated LRTIs.