Long-Term Immunity after Vaccination against Yellow Fever in Korean Travelers

• DOI: 10.7883/yoken.jjid.2023.290
• Publication Date: 2024-11-28T22:13:00Z
• Authors: Jihye Um; Chad Douglas Nix; William Bill Messer; Yerun Zhu; Jun-Sun Park; Matthew Harmon Co...; BumSik Chin
• Keywords: Herd Immunity; Yellow fever vaccine

While a live-attenuated Yellow fever (YF) vaccine is known to elicit durable immunity, antibody titers may wane after vaccination. This study evaluated the long-term immunity vaccination against YF among individuals who reside in Korea and received with virus-17D prior international travel. Serum was collected between December 2018 2019 at National Medical Center, Republic of from recipients were vaccinated more than five years sample collection. Long-term assessed using three serological assays: IgG enzyme-linked immunosorbent assay (ELISA), immunofluorescence (IFA), focus reduction neutralization test (FRNT). Sixty seven subjects enrolled. The overall positivity rates for FRNT