- Plant-Microbe Interactions and Immunity
- Legume Nitrogen Fixing Symbiosis
- Plant Parasitism and Resistance
- HIV Research and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Immune Cell Function and Interaction
- Plant Pathogenic Bacteria Studies
- Transgenic Plants and Applications
- Plant Pathogens and Fungal Diseases
- Plant pathogens and resistance mechanisms
University of North Carolina at Chapel Hill
2019-2022
Howard Hughes Medical Institute
2019-2022
Significance In natural environments, plants establish intimate interactions with a wide diversity of microbes. It is unknown, however, how microbiota composed commensal bacteria colonize roots in the face sophisticated plant immune system that evolved to recognize microbial-associated molecular patterns. We investigate interaction between function and root microbiota. report root-associated actively suppress host response context community. Suppressors nonsuppressors co-occur microbiome...
The major feature of HIV-1 pathogenesis is the induction an immunodeficient state in face enhanced inflammation. However, for many those infected, there can be impact on central nervous system (CNS) resulting a wide range neurocognitive defects.