A5003066907- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Myasthenia Gravis and Thymoma
- Transplantation: Methods and Outcomes
- Head and Neck Cancer Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Meningioma and schwannoma management
- Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Pleural and Pulmonary Diseases
- interferon and immune responses
- Cancer-related Molecular Pathways
- Ubiquitin and proteasome pathways
- Advanced Radiotherapy Techniques
- Colorectal and Anal Carcinomas
- Renal Transplantation Outcomes and Treatments
University of Ulsan
2015-2025
Asan Medical Center
2015-2025
Ulsan College
2015-2025
Samsung Medical Center
2011-2024
Sungkyunkwan University
2011-2020
San Diego Cardiac Center
2016
The International Association for the Study of Lung Cancer (IASLC) proposed further subdivisions pathological N1 (pN1) and pN2 by including location number involved lymph node (LN) stations. We adopted subdivided N descriptors reclassified them according to LN zones or stations, compared discrimination abilities 2 classifications.A retrospective analysis was carried out on patients who underwent complete resection with systematic dissection non-small cell lung cancer diagnosed as stages...
Abstract OBJECTIVES Although the standard treatment for pathological N2 (pN2) non-small-cell lung cancer (NSCLC) patients is definitive chemoradiation, surgery can be beneficial resectable pN2 disease. Herein, we report long-term clinical outcomes of upfront followed by adjuvant selected with METHODS We performed a retrospective analysis disease who underwent as first-line therapy. Multivariable Cox regression was used to identify significant factors overall survival (OS) and recurrence-free...
Frequent recurrence and metastasis caused by cancer stem cells (CSCs) are major challenges in lung treatment. Therefore, identifying characterizing specific CSC targets crucial for the success of prospective targeted therapies. In this study, it is found that upregulated TOR Signaling Pathway Regulator-Like (TIPRL) CSCs causes sustained activation calcium/calmodulin-dependent protein kinase 2 (CaMKK2) signaling pathway binding to CaMKK2, thereby maintaining stemness survival. CaMKK2-mediated...
Sublobar resection has been established as an acceptable treatment for early-stage non-small cell lung cancer (NSCLC). As a result, preoperative prediction of lymph node (LN) metastasis is becoming important factor in determining surgical strategy. This study aimed to investigate the predictive accuracy consolidation tumor ratio (CTR) and maximum standardized uptake value (maxSUV) primary LN patients with clinical stage IA NSCLC. We performed retrospective analysis using data from 1,338...
The International Association for the Study of Lung Cancer introduced 8th edition tumor, node, and metastasis (TNM) staging system lung cancer. In this study, we validated TNM compared its discrimination power with that previous 7th edition.A retrospective analysis was carried out on patients who underwent complete resection systematic lymph node dissection non-small cell cancer (NSCLC) between 2006 2015 at a tertiary referral center in Seoul, South Korea. Cox regression model used to...
SUMMARY Robots are increasingly used in minimally invasive surgery. We evaluated the clinical benefits of robot-assisted esophagectomy (RAMIE) comparison with conventional open esophageal From 2012 to 2016, 371 patients squamous cell carcinoma underwent an Ivor Lewis or McKeown procedure at our institution. Of these, 130 laparoscopic gastric conduit formation followed by RAMIE, whereas 241 surgery, including laparotomy and (OE). compared short- long-term outcomes these using propensity...
BACKGROUND. Prognostic factors on preoperative CT in stage IA non-small cell lung cancer (NSCLC) may help select patients for sublobar resection or lobectomy. OBJECTIVE. The purpose of this study was to identify features predictive pathologic lymphovascular invasion (LVI) NSCLC and evaluate the features' prognostic value who undergo resection. METHODS. This retrospective included 904 (mean age, 62.0 years; 453 men, 451 women) underwent lobectomy (n = 574) 330) NSCLC. Two thoracic...
We aimed to elucidate the prognostic value of tumor regression grade (TRG) combined with lymph node status compared 8th edition ypTNM staging system in patients advanced esophageal squamous cell cancer (ESCC) after neoadjuvant chemoradiotherapy (nCRT).We enrolled 325 ESCC who underwent nCRT followed by complete resection. adopted modified Schneider TRG system, high (ypT0N0), mid (ypT0N+ or ypT + N0), and low (ypT N+). After developing a multivariable Cox model, discrimination ability ypStage...
Curative resection is not indicated for non-small cell lung cancer (NSCLC) with pleural seeding, which classified as stage IV (M1a) disease. However, some patients a presumably resectable main tumor are diagnosed localized seeding during surgery.A retrospective analysis was performed of 3,975 who underwent surgery NSCLC from 2000 to 2011. Among these cases, 78 (2.0%) had unexpected detected surgery. Exploration biopsy in 42 (exploration-only group) and pulmonary resection, including the...
Abstract Airway complications may occur after lung transplantation and are associated with considerable morbidity mortality. We investigated the incidence, risk factors, clinical characteristics of these complications. retrospectively reviewed medical records 137 patients who underwent between 2008 2021. The median follow-up period was 20 months. Of patients, 30 (21.9%) had postoperative airway complications, which 2 two different types most common complication bronchial stenosis, affecting...
In 2003, robot-assisted minimally invasive esophagectomy (RAMIE) was first reported to overcome the technical limitations of esophagectomy. RAMIE requires repeated modifications set up robotic system, and sufficient experience is required gain proficiency. This study aimed identify learning periods outcomes for esophageal carcinoma.We retrospectively reviewed 500 consecutive cases cancer from December 2008 February 2021. The curve identified using cumulative sum analysis.In a total patients,...
Thymic cysts are a rare benign disease that needs to be distinguished from low-risk thymoma. [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed (CT) is non-invasive imaging technique used in the differential diagnosis of thymic epithelial tumours, but its usefulness for remains unclear. Our study evaluated utility visual findings and quantitative parameters [18F]FDG PET/CT differentiating between thymomas. Patients who underwent preoperative followed by thymectomy mass...
Although robot-assisted minimally-invasive esophagectomy (RAMIE) surgeries are expanding clinically, few studies have reported patients with locally-advanced esophageal cancer who underwent neoadjuvant chemoradiation therapy (nCRT).From 2013 to 2017, 219 squamous cell carcinoma RAMIE and 35 of them received nCRT at our institution. During the period, 289 conventional open (OE) 111 nCRT. We compared postoperative mortality morbidity OE after nCRT.In nCRT, groups had similar operative time,...
Background: Although there are numerous postoperative surveillance guidelines for non-small cell lung cancer (NSCLC), most recommend the same protocol patients with different recurrence dynamics. In this study, we investigated dynamics of NSCLC according to their clinical factors.
Abstract OBJECTIVES To investigate lymph node (LN) metastasis according to tumour location and assess the impact of lobe-specific LN dissection on survival in stage IA non-small-cell lung cancer (NSCLC). METHODS We retrospectively analysed data patients with clinical NSCLC treated lobectomy systematic at Asan Medical Center (Seoul, Korea) between June 2005 April 2017. Patients who received neoadjuvant therapy had multiple primary tumours or missed follow-up during first postoperative year...