Introduction: Cutaneous metastases represent 2% of skin tumors, with an overall incidence 5.3%. Although rare, clinical presentations cutaneous metastasis vary and can be mistaken for benign malignant conditions. Methodology: This was a descriptive, retrospective review all patients diagnosed seen at the Department Dermatology from January 2013 to December 2019. Clinical histopathologic data were collated medical records, slides retrieved review. Results: A total 115 included 122 reviewed....

Dermatofibroma (DF) is a common, benign fibrohistiocytic tumor with unknown pathogenesis. There are multiple uncommon histologic variants of DF reported in literature, one which hemosiderotic DF. It can variably present as pigmented papule or nodule commonly located on the lower extremities. Hemosiderotic remains to be underreported Philippines despite widely available dermatopathology services country.

Acquired perforating dermatosis represents one of the skin disorders showing transepidermal elimination dermal contents. Dermoscopy concentric zones a central keratotic plug, white-gray structureless area and peripheral brown pigmentation may aid in diagnosis sample selection for biopsy.

A 29-year-old male with eleven-year history of hyperkeratotic papules and speckled pigmentation developed cutaneous squamous cell carcinoma. Arsenicosis was confirmed by elevated hair arsenic level, histopathologic findings arsenical keratosis one lesion showing carcinoma-in-situ. Chronic exposure has been found to activate inflammatory carcinogenic pathways leading development pre-malignant malignant lesions. multi-disciplinary approach involving healthcare specialists environmentalists is...

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A 40-year old Filipino male was managed as a case of clinically amyopathic dermatomyositis (CADM) after presenting only with pruritic photodistributed symmetric erythematous-violaceous patches, nail fold telangiectasia and the pathognomonic Gottron papules. There no clinical evidence muscle involvement. The patient shortly presented metastatic undifferentiated carcinoma on cervical lymph nodes. This demonstrates that can present uncommonly CADM associated carcinoma.

Calcemic uremic arteriolopathy or calciphylaxis is an uncommon disorder presenting clinically as skin ischemia and necrosis, histologically vascular calcification thrombosis of dermal subdermal vasculature. This study described two Filipino females with end-stage renal disease on chronic dialysis non-healing ulcers the lower extremities a result in vessels dermis subcutaneous fat associated necrosis. Current understanding its various histologic features was reviewed for proper diagnosis.

We report a 23-year-old male with lepromatous leprosy atypically presenting 5-year history of asymptomatic, verrucous papules, and nodules. Human Immunodeficiency Virus (HIV) testing was positive depressed CD4 count. In HIV/leprosy co-infection, most the documented patients were diagnosed paucibacillary as immune reconstitution disease (IRD) from treatment-induced immunological recovery. Rarely, multibacillary is encountered in setting untreated, severe immunodeficiency. Atypical clinical...

We report the first published case of multiple eruptive myxoid dermatofibroma (MEMDF) in a male with chronic hepatitis B infection presenting lesions showing marked deposits dermal mucin. Alcian blue and immunohistochemistry confirmed diagnosis dermatofibroma. Further work-up showed asymptomatic without cirrhosis. This highlights an extremely rare histologic variant importance screening for altered immunity patients dermatofibromas.

Chromoblastomycosis is an endemic mycoses which has been misdiagnosed or underdiagnosed in the past. This may be due to clinicopathologic characteristics that it shares with other neglected tropical diseases such as leprosy and cutaneous tuberculosis. Correlating clinical findings histopathologic cues will lead clinicians correct diagnosis subsequent treatment success.

A 65-year-old female with chronic kidney disease (CKD) presented a six-month history of asymptomatic translucent skin-colored and yellow plaques on the face. Similar papules nodules were noted in oral cavity eyelid margins. Biopsies taken from face showed homogeneous eosinophilic deposits clefts dermis consistent colloid milium. The patient was treated fractional surgical carbon dioxide (CO2) laser improvement after one session.

A 33-year-old male had a 22-year history of generalized xanthogranulomas but normal lipid profile. He also developed ulcerating plaques on his arm and back that were consistent with cutaneous tuberculosis histopathologic polymerase chain reaction PCR studies. In normolipemic patient xanthogranulomas, reactive granulomatous response histiocytes to infection is explored since these share common CD 14+ precursor the macrophages are vital in tuberculosis.

A 5-year-old female presented a 4-year history of generalized well-demarcated asymptomatic brown to dark thin verrucous plaques with Blaschkoid distribution. Histopathology was consistent an epidermal nevus. Patient diagnosed have systematized Due the extent lesions, surgical management not feasible. Hence acitretin given which showed partial decrease in thickness lesions.

Verrucous carcinoma is an uncommon low-grade well-differentiated malignant neoplasm that commonly arises on acral and mucosal sites. It often both clinically histologically misdiagnosed because of its slow growth low cytologic atypia, respectively. We describe the case a 74-year-old female with papillomatous mass arising muscle flap skin graft site left foot had delay in diagnosis for more than 30 years. This highlights verrucous as consideration clinical histologic differential diagnoses...

T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive malignancy. Diagnosis achieved by proper interpretation of the morphology, immunophenotype, cytogenetics obtained. It highly responsive to single agent alemtuzumab providing treatment once diagnosed dramatically improves survival. A 49-year-old Filipino female, with T-PLL, morphologic remission after six cycles cyclophosphamide, doxorubicin, vincristine, prednisone. After three months, she presented diffuse generalized...

The creation of a department often happens ‘de novo’. For most institutions, they were born as while for Dermatology in the UP College Medicine, Philippine General Hospital, it took almost two decades to become one.
 Unit was established by Dr. Perpetuo Gutierrez under Department Medicine 1922. He pioneer and known be Father he paved way development specialty our country.
 Fast forward February 2020 five section division chiefs later, Division has finally - 21st Medicine.
 In...

A 37-year-old Filipino man presented with a 9-month history of sagging skin progressing cephalocaudally from the chin and neck to axillae, side trunk, pelvic area. This was followed by 2-month increasing serum creatinine levels associated periorbital bipedal edema, generalized weakness, decreased appetite, vomiting, headache. Subsequently, skin-colored, non-tender sac-like plaques appeared on abdomen, inguinal, intergluteal areas. Histopathology latter lesions showed increased spaces between...

Dedifferentiated liposarcoma is a soft tissue sarcoma of adipocytic lineage. Histopathology and immunohistochemistry are essential for diagnosis. A 51-year-old Filipino woman presented with rapidly enlarging left gluteal tumor. revealed multilobulated tumor having prominent myxoid stroma numerous stellate-shaped, atypical cells bearing mitotic figures. Other lobules were composed sheets pleomorphic cells, The stained positively alcian blue, vimentin, MDM2 p16 stains. immunohistochemical...