A5086220041- Coronary Interventions and Diagnostics
- COVID-19 Clinical Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Long-Term Effects of COVID-19
- Acute Myocardial Infarction Research
- COVID-19 and healthcare impacts
- Blood Pressure and Hypertension Studies
- Nitric Oxide and Endothelin Effects
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Laser Applications in Dentistry and Medicine
- Cardiovascular Health and Disease Prevention
- Hormonal Regulation and Hypertension
- Heart Failure Treatment and Management
- Peripheral Artery Disease Management
- Nutrition and Health Studies
- Cardiovascular Issues in Pregnancy
- Neonatal Respiratory Health Research
- Eicosanoids and Hypertension Pharmacology
- Cardiac and Coronary Surgery Techniques
- Hematopoietic Stem Cell Transplantation
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Protease and Inhibitor Mechanisms
Wrocław University of Science and Technology
2023-2025
AGH University of Krakow
2023-2025
Military Hospital
2024-2025
Wroclaw Medical University
2014-2024
4. Wojskowy Szpital Kliniczny z Polikliniką
2024
Wrocław University of Environmental and Life Sciences
2024
Witelon State University of Applied Sciences in Legnica
2023
Szpital Kliniczny Nr 1 we Wrocławiu
2021
Wroclaw Research Centre EIT+ (Poland)
2014-2018
University of Saskatchewan
2009-2013
Patients with heart failure (HF) are at high risk of unfavorable courses COVID-19. The aim this study was to evaluate characteristics and outcomes COVID-19 patients HF.Data hospitalized in a tertiary hospital Poland between March 2020 May 2021 laboratory-confirmed were analyzed. population divided into HF group (patients history HF) non-HF group.Out 2184 (65 ± 13 years old, 50% male), 12% had HF. from the older, more often males, comorbidities, dyspnea, pulmonary peripheral congestion,...
Due to the molecular mechanisms of action antidiabetic drugs, they are considered be effective in treatment both COVID-19 and post-COVID-19 syndromes. The aim this study was determine effect administering insulin metformin on mortality patients with type 2 diabetes (T2DM) symptomatic use logistic regression models. association between death weak could not included multivariate model. However, interaction drugs other factors, including remdesivir low-molecular-weight heparin (metformin), age...
The aim of our study was to evaluate if endothelial-dysfunction (ED) occurs in patients with primary Sjogren syndrome (pSS) and whether it is associated the disease characteristics activity. A total 46 pSS 30 controls, without known cardiovascular disease, were enrolled this study. flow-mediated-dilation (FMD) brachial artery, plasma concentrations nitric oxide (NO) metabolic pathway (ADMA, L-arginine, SDMA, cGMP), markers endothelial inflammatory function (PAI-1, sE-selectin) angiogenesis...
Low-level laser therapy (LLLT) has become an important part of the therapeutic process in various diseases. However, despite broad use LLLT everyday clinical practice, full impact on cell life processes not been fully understood. This paper presents current state knowledge concerning mechanisms action cells. A better understanding molecular occurring within after irradiation may result introducing numerous novel applications and potentially increases safety profile this therapy.
Background. The nutritional status of patients in hospitals has a significant impact on the effectiveness treatment, occurrence complications, and length hospitalization. purpose this study was to evaluate with heart failure (HF) its patient outcomes. Material Methods. This included 213 (153 men, 71.8%) aged 74.7 ± 14.3 years treated for HF at cardiology clinic 4th Military Clinical Hospital between 2018 2021. Sociodemographics, clinical data, Model End-Stage Liver Disease (MELD),...
Background/Objectives: Quality of life (QoL) is recognized as a clinically significant outcome measure among patients with aortic stenosis (AS). However, there no validated, AS-specific questionnaire available in Poland for assessing the QoL AS patients. The aim study was to determine psychometric properties Polish version Toronto Aortic Stenosis Life Questionnaire (the TASQ). Methods: involved 113 severe (including 59 women), aged 74 82 years [mean age 77 years], hospitalized at department...
Damage to cardiac contractile proteins during ischemia followed by reperfusion is mediated reactive oxygen species such as peroxynitrite (ONOO−), resulting in impairment of systolic function. However, the pathophysiology dysfunction only, before reperfusion, remains unclear. We suggest that increased ONOO− generation leads nitration/nitrosylation myosin light chain 1 (MLC1) and its degradation matrix metalloproteinase-2 (MMP-2), which cardiomyocyte contractility. also postulate inhibition...
Hypoxia followed by reoxygenation (H-R) observed during perinatal asphyxia is a serious complication with high mortality and morbidity rates that may cause adverse cardiovascular effects in neonates. Our aim was to determine if oxidative stress related H-R induces peroxynitrite-dependent modifications of the cardiac contractile protein, myosin regulatory light chain 2 (MLC2), whether this associated development systolic dysfunction. Twelve newborn piglets were acutely instrumented for...
The unprotected calcified Left Main disease represents a high-risk subset for percutaneous coronary intervention (PCI), and it is associated with higher number of periprocedural complications an increased rate in-stent thrombosis restenosis. Adequate lesion preparation plays crucial role in achieving favorable PCI outcome. Rotational Atherectomy (RA) well-established plaque-modifying method; nevertheless, the data regarding effectiveness RA LM diseases scarce. Recently, novel...
Abstract One of the major pathomechanisms COVID-19 is interplay hyperinflammation and disruptions in coagulation processes, involving thrombocytes. Antiplatelet therapy (AP) by anti-inflammatory effect inhibition platelet aggregation may affect these pathways. The aim this study was to investigate if AP has an impact on in-hospital course medium-term outcomes hospitalized patients. population (2170 patients: mean ± SD age 60 19 years old, 50% male) divided into a group 274 patients receiving...