A5052468882- Neonatal and Maternal Infections
- Streptococcal Infections and Treatments
- Neonatal Respiratory Health Research
- Maternal and Neonatal Healthcare
- Hematopoietic Stem Cell Transplantation
- Infant Development and Preterm Care
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Neonatal and fetal brain pathology
- Breast Implant and Reconstruction
- Immune Cell Function and Interaction
- Neuroscience of respiration and sleep
- Orthodontics and Dentofacial Orthopedics
- Cytomegalovirus and herpesvirus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Obstructive Sleep Apnea Research
- Breast Cancer Treatment Studies
- Temporomandibular Joint Disorders
- Anesthesia and Neurotoxicity Research
- Renal and Vascular Pathologies
- T-cell and B-cell Immunology
- Anesthesia and Pain Management
- Infant Nutrition and Health
- Dental Radiography and Imaging
- Anesthesia and Sedative Agents
Azienda Ospedaliero-Universitaria di Modena
2010-2024
University of Modena and Reggio Emilia
2021-2024
Piaggio (Italy)
2024
Comune di Venezia
2024
Universidad Alfonso X el Sabio
2020-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2024
Procter & Gamble (Italy)
2023
University of Cagliari
2020
Faculty (United Kingdom)
2020
Universidad de Salamanca
2020
There is insufficient population-based data on group B streptococcus (GBS) late-onset disease (LOD). Risk factors and routes of GBS transmission are poorly understood.A prospective, cohort study was conducted to collect incidence LOD evaluate infections over an 8-year period (2003-2010). Starting from January 2007, maternal rectovaginal breast milk cultures were routinely collected confirmation the diagnosis assess culture status.The rate 0.32 per 1000 live births (1.4 0.24 for preterm term...
The published data to support recommendations for prevention and management of well-appearing at-risk newborns (WAARNs) early-onset sepsis (EOS) are limited.Retrospective cohort study comparing two different strategies managing WAARNs (≥ 35 weeks' gestation) during a 6-year period (Period 1, from 2005 2007; Period 2, 2009 2011). were defined as healthy-appearing neonates evaluated because risk factors EOS. Laboratory evaluation plus simplified physical examination 1) was compared with alone...
To investigate whether serial physical examinations (SPEs) are a safe tool for managing neonates at risk early-onset sepsis (EOS).This is retrospective cohort study of (≥ 34 wks' gestation) delivered in three high-volume level IIIbirthing centres Emilia-Romagna (Italy) during 4-mo period (from September 1 to December 31, 2015). Neonates EOS were managed according the SPEs strategy, these carried out turn by bedside nursing staff and physicians. A standardized form detailing general...
Background: Data regarding the minimum duration of intrapartum antibiotic prophylaxis (IAP) required for preventing group B Streptococcus (GBS) early-onset sepsis are conflicting. Understanding factors that influence neonatal colonization (NC) might help us understand associated with failure prophylaxis. Methods: This is a 14-month prospective cohort study conducted at single tertiary care center screening-based strategy. Women were enrolled if they had ≥35 weeks' gestation and GBS-positive...
Objective: This study aims to evaluate safety and success rates of lumbar puncture (LP) identify factors associated with adverse events or failure LP in infants. Methods: two-center prospective observational investigated infants younger than 90 days age who underwent LP. Need for resuscitation oxygen desaturation (SpO 2 < 90%), bradycardia intraventricular hemorrhage were considered events. failed if cerebrospinal spinal fluid was not collected had traces blood. Logistic regression...
There are wide variations in antibiotic use neonatal intensive care units (NICUs). Limited data available on antimicrobial stewardship (AS) programs and long-term maintenance of AS interventions preterm very-low-birth-weight (VLBW) infants.
Background: Prevention of residual cases neonatal group B streptococcus (GBS) early-onset disease (EOGBS) has become a goal in the past decade. This study is aimed at evaluating changes incidence EOGBS over 9-year period after implementation screening-based approach and comparing 2 different protocols for managing healthy-appearing at-risk newborns (ARNs). Methods: A strategy was introduced Emilia-Romagna (Italy) 2003. prospective, cohort conducted from 2003 to 2011; culture-proven were...
Background: Group B Streptococcus (GBS) is a leading cause of neonatal bacterial infections. Early-onset infections have decreased in recent years but, despite considerable efforts poured into prevention, cases continue to occur. Objectives: To analyze trends and identify determining factors for the persistence GBS evaluate impact antenatal screening intrapartum chemoprophylaxis on clinical presentation infection. Methods: A prospective cohort, population-based study has been ongoing...
Gestational SARS-CoV-2 infection can impact maternal and neonatal health. The virus has also been reported to cause newborn sensorineural hearing loss, but its consequences for the auditory system are not fully understood.The aim of this study was evaluate during pregnancy on newborn' function first year life.An observational conducted from 1 November 2020 30 2021 at University Modena Hospital. All newborns whose mother had infected by were enrolled underwent audiological evaluation birth...
Objective. Current guidelines for prevention of group B streptococcus (GBS) early-onset infection recommend to administer antibiotic during labor at least 4 h prior delivery (adequate prophylaxis). We aimed determine if neonatal GBS colonization may be significantly decreased in case inadequate (<4 h) duration ampicillin prophylaxis.Methods. In prospective, cohort study, 167 infants born culture-positive mothers without additional risk factors were enrolled. Cultures collected both, 10–24...
High-dose chemotherapy followed by reinfusion of autologous stem cells harvested from peripheral blood has been increasingly applied for a variety disorders. The critical importance cell dose in the clinical outcome, after transplant, motivated need to develop techniques aimed at reducing losses and increasing reproducibility.The aim this study is evaluate efficacy Sepax S-100 device process thawed HPC-A products comparison with manual procedure.We have analysed viability, total nucleated...
Abstract Because emergency departments are often the first point of contact for victims violence, it is critical to provide appropriate treatment in compliance with all necessary medicolegal precautions. For this reason, a randomized controlled trial was conducted at Policlinico Hospital Milan (Italy) which an intervention group (12 physicians) received 6-h course on clinical forensic medicine and their performance procedures claimed cases violence compared that control (13 by means 16-item...
Click to increase image sizeClick decrease size Notes1. AAC system: An integrated group of components, including the symbols, aids, strategies and techniques used by individuals enhance communication. The system serves supplement any gestural, spoken, and/or written communication abilities (American Speech‐Language Hearing Association, Citation1991).
Neonatal sepsis is an important cause of morbidity and mortality in neonatal intensive care units (NICUs). Continuous evaluation antimicrobial resistance (AMR) profiles advised to implement stewardship (AMS) programs establish effective empiric antibiotic protocols. AMS may reduce AMR NICUs improve outcomes. In this retrospective observational study, we report data on culture-positive sepsis, assessing differences after the implementation program (2011-2016 vs. 2017-2022). A total 215...
The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations preventing GBS-EOD lacking.This was a 3-month retrospective area-based study including all regional deliveries ≥35 weeks' gestation (in 2012). sensitivity, specificity, positive negative predictive values, odds ratio receiver operating characteristic (ROC) curve...