- SARS-CoV-2 and COVID-19 Research
- interferon and immune responses
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Lung Cancer Treatments and Mutations
- COVID-19 Clinical Research Studies
- Peptidase Inhibition and Analysis
- Lung Cancer Diagnosis and Treatment
- Influenza Virus Research Studies
- Pancreatic and Hepatic Oncology Research
Qilu Hospital of Shandong University
2025
Nanjing Agricultural University
2024
Occult liver metastases in patients with pancreatic ductal adenocarcinoma (PDAC) affects treatment strategies and prognosis. Diffusion-weighted imaging (DWI), including non-Gaussian DWI may help to evaluate tumor biological behavior. To the diagnostic value of parameters predicting occult PDAC. Prospective. 115 participants pathologically confirmed PDAC (male = 71, mean age 59.8 ± 9.9 years). metastasis was defined as those detected by CT or MRI within 6 months pancreatectomy. DWI,...
Middle East respiratory syndrome coronavirus (MERS-CoV) and the pangolin MERS-like MjHKU4r-CoV-1 employ dipeptidyl peptidase 4 (DPP4) as an entry receptor. could infect transgenic mice expressing human DPP4. To understand mechanism of into cells, we determined crystal structures receptor binding domain (RBD) spike protein bound to DPP4 (hDPP4) Malayan (MjDPP4), respectively. The overall hDPP4-binding mode RBD is similar that MERS-CoV RBD. shows higher affinity hDPP4 compared bat...