A5022291616- Reproductive tract infections research
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Syphilis Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Bacterial Infections and Vaccines
- Drug-Induced Adverse Reactions
- Colorectal Cancer Screening and Detection
- HIV Research and Treatment
- Blood groups and transfusion
- Pelvic floor disorders treatments
- HIV/AIDS drug development and treatment
- Pharmaceutical studies and practices
- Genetic factors in colorectal cancer
- Respiratory and Cough-Related Research
Rush University Medical Center
2022
Office of Infectious Diseases
2019
University of California, Los Angeles
2018-2019
UCLA Health
2019
Background Gay, bisexual, transgender, and homeless youth are at risk of sexually transmitted infections. As part an adolescent human immunodeficiency virus prevention study, we provided same-day Chlamydia trachomatis (CT) Neisseria gonorrhoeae (NG) testing treatment. We aimed to evaluate the feasibility effectiveness CT NG treatment on proportion participants receiving timely Methods recruited adolescents with high sexual behaviors aged 12 24 years from shelters, lesbian, gay, transgender...
Background Gay, bisexual, and transgender youth homeless are at high risk for sexually transmitted infections (STIs). However, little recent data exist describing STI positivity by anatomical site among those groups. We determined the of Chlamydia trachomatis (CT) infection, Neisseria gonorrhoeae (NG) syphilis antibody reactivity lesbian, gay, transgender, youth. Methods recruited 1,264 adolescents with behavior aged 12 to 24 years from shelters, organizations, community health centers,...
Objective: Our goal was to evaluate knowledge and testing preferences for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV) infections.Participants: We surveyed female undergraduates attending the University of California, Los Angeles, in May 2017.Methods: Using an online survey, we collected demographic information on 793 participants' health care seeking behavior, sexual activity, sexually transmitted infection (STI) knowledge, STI screening preferences....
Pre-exposure prophylaxis (PrEP) to prevent human immunodeficiency virus (HIV) is extremely effective when taken correctly, though grossly under-prescribed for at-risk patients. We initiated a best practice advisory (BPA) in the Epic electronic medical record (EMR) identify patients who met criteria PrEP use. evaluated this model determine its effectiveness identifying and use by providers increasing prescription of PrEP. The BPA fired 145 times with five total new prescriptions. Over half...
Background Human papillomavirus (HPV) vaccination coverage continues to be at low moderate levels throughout the United States. HPV infection is linked multiple types of cancers resulting in high economic and health burden. We aimed estimate excess number cancer cases associated medical costs due current for a 20-year-old birth cohort California. Methods estimated lifetime caused by vaccine-preventable strains 20 year-olds then that which would occur 2017 compared with an optimal 99.5%. By...
Abstract Background Human immunodeficiency virus (HIV)-1 RNA quantification is the primary method of monitoring response to antiretroviral therapy. In U.S. viral testing recommended for all HIV-infected patients at entry into care, initiation or modification therapy, and on a regular basis thereafter. HIV-1 DNA may pose additional advantages. For example, proviral predict early loss suppression. The Cepheid® (Sunnyvale, CA) Qualitative (HIV Qual) assay detects total nucleic acid both...
<h3>Background</h3> <i>Chlamydia trachomatis</i> (CT) and <i>Neisseria gonorrhoeae</i> (NG) disproportionately affect adolescents, however, many adolescents receive infrequent sexually transmitted infection (STI) testing. Gay, bisexual, transgender, homeless youth are at increased risk for STIs. Currently, the Centers Disease Control Prevention recommend only annual screening of CT/NG all active gay, other men who have sex with (MSM). <h3>Methods</h3> We recruited aged 12–24 years from...
<h3>Background</h3> <i>Chlamydia trachomatis</i> (CT) and <i>Neisseria gonorrhoeae</i> (NG) are the most common sexually transmitted infections (STIs). Lesbian, gay, bisexual, transgender, queer (LGBTQ) homeless youth often report risk-taking behaviors such as higher number of sex partners condom-less sex, yet they have decreased access to healthcare services. Providing treatment following testing can reduce transmission infection risk developing complications. As part a large, adolescent...
<h3>Background</h3> <i>Neisseria gonorrhoeae</i> (NG) has developed resistance to most antibiotics, making it increasingly difficult treat. Molecular methods have been used predict antimicrobial susceptibility based on the <i>gyr</i>A codon serine 91 and mosaic XXXIV allele penicillin-binding protein 2 (<i>pen</i>A) gene using Roche Cobas APTIMA clinical specimens. We aimed determine if same could be successfully remnant NG-positive Cepheid Xpert® <h3>Methods</h3> tested pharyngeal, rectal,...
Abstract Background Penicillin allergy is the most commonly reported drug in pediatric population. However, reports do not represent true IgE-mediated or late-onset severe hypersensitivity reactions. False labels can lead to unnecessarily broad and/or non-first line antibiotic utilization, development of resistance, adverse side effects, and have implications for use antimicrobials adulthood. In an effort decrease inappropriate labeling, we implemented a multipronged approach evaluation...