A5102809075- Lipoproteins and Cardiovascular Health
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Cardiovascular Health and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Cardiac Imaging and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Diabetes Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Pharmaceutical Economics and Policy
- Sex and Gender in Healthcare
- Cardiac Arrhythmias and Treatments
- Cardiovascular Disease and Adiposity
- Fatty Acid Research and Health
- Cardiac and Coronary Surgery Techniques
- Coronary Interventions and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Alcohol Consumption and Health Effects
- Cardiac pacing and defibrillation studies
- Chronic Disease Management Strategies
- Heart Rate Variability and Autonomic Control
University of Pittsburgh Medical Center
2021-2025
University of Pittsburgh
2020-2025
UPMC Health System
2021-2024
Henry Ford Health System
2024
Magna International (Germany)
2021
MedStar Health
2006-2012
Norton Sound Health Corporation
2008
Cornell University
2008
MedStar Washington Hospital Center
1999-2008
MedStar Union Memorial Hospital
2005
Background Assessment of the social determinants post-hospital cardiac care is needed. We examined association and predictive ability neighborhood-level (area deprivation index, ADI), readmission risk, mortality for heart failure, myocardial ischemia, atrial fibrillation. Methods Results Using a retrospective (January 1, 2011-December 31, 2018) analysis large healthcare system, we assess ADI on 30-day 1-year following hospitalization. Cox proportional hazards models analyzed time-to-event....
BACKGROUND: Hypertensive disorders of pregnancy (HDP) are associated with subsequent adverse cardiac remodeling and cardiovascular disease. The role myocardial microvascular disease among individuals HDP left ventricular (LV) as a potential link to is unknown. We aimed determine whether history have coronary dysfunction measured by flow reserve 8 10 years after delivery correlates LV remodeling. METHODS: Individuals pregnancies delivered from 2008 2010 underwent burst-replenishment contrast...
Pulmonary hypertension (PH) is a vascular disease characterized by elevated pulmonary arterial pressure, leading to right ventricular failure and death. Pathogenic features of PH include endothelial apoptosis inflammation, which drive remodeling increased pressure. Re-analysis the whole transcriptome sequencing comparing human cells (PAECs) isolated from control patients identified AREG , encodes Amphiregulin, as key survival factor. PAECs mice exhibited down-regulation its receptor...
Current American College of Cardiology/American Heart Association guidelines recommend using the 10-year atherosclerotic cardiovascular disease (ASCVD) risk to guide statin therapy for primary prevention. Real-world data on adherence and consequences nonadherence in are limited. We investigated guideline-directed intensity (GDSI) associated outcomes a large health care system, stratified by ASCVD risk.Statin prescription patients without coronary artery disease, peripheral vascular or...
Elderly patients are less likely to undergo surgery for an acute type A aortic dissection (ATAAD). This study aims understand the risks of surgical treatment in 75 and older.
This article is a report of the design and methods Genetics Coronary Artery Disease in Alaska Natives (GOCADAN) Study. longitudinal, population-based study was initiated to investigate genetic determinants cardiovascular disease its risk factors. Between October 2000 April 2004, this family enrolled 1,214 Eskimos from several coastal villages Norton Sound region Western Alaska. Examinations included physical, laboratory determinations, measures subclinical disease. will generate genome-wide...
J Clin Hypertens (Greenwich). ****;**:**–**. ©2011 Wiley Periodicals, Inc. It is unknown what role uric acid (UA) may play in the increasing rates of cardiovascular disease (CVD) among Alaska Eskimos. UA associated with both hypertension (HTN) and chronic kidney (CKD). The authors analyzed 1078 Genetics Coronary Artery Disease Natives (GOCADAN) participants. Estimated glomerular filtration rate (eGFR) was calculated from serum creatinine measures using Modification Diet Renal equation. CKD...
Neighborhood socioeconomic status is associated with health outcomes. Cardiac rehabilitation (CR) provides a cost-effective, multidisciplinary approach to improve outcomes in cardiovascular disease. We aimed evaluate the association of Area Deprivation Index (ADI), marker neighborhood social composition, risk recurrent and assessed modifying effect CR.We identified patients primary diagnosis (1) myocardial infarction or (2) incident heart failure (HF) admitted large-sized regional center...
The risk factor (RF) burden, clinical course, and long-term outcome among patients with atrial fibrillation (AF) aged <65 years is unclear.
In the US, women have similar cardiovascular death rates as men. However, less is known about sex differences in statin use for primary prevention and associated atherosclerotic disease (ASCVD) outcomes.
Objective To determine the long-term impact of developing acute renal failure (ARF) on survival after open aortic arch reconstruction for type A dissection (ATAAD). Methods This was an observational study consecutive surgeries from 2007 to 2021. Patients with ATAAD were identified via a prospectively maintained institutional database and stratified by presence or absence postoperative ARF (by RIFLE criteria). Kaplan–Meier estimation multivariable Cox regression analysis performed. Results...