A5079123755- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Electrochemical Analysis and Applications
- Organic Light-Emitting Diodes Research
- Luminescence and Fluorescent Materials
- X-ray Diffraction in Crystallography
- Trauma and Emergency Care Studies
- Crystallization and Solubility Studies
- Service-Learning and Community Engagement
- Evaluation of Teaching Practices
- Molecular Junctions and Nanostructures
- RNA Interference and Gene Delivery
- Radical Photochemical Reactions
- Innovative Teaching and Learning Methods
- Emergency and Acute Care Studies
- Migration and Labor Dynamics
- CO2 Reduction Techniques and Catalysts
- Advanced Photocatalysis Techniques
- Nanopore and Nanochannel Transport Studies
- MicroRNA in disease regulation
- Microfluidic and Capillary Electrophoresis Applications
- 2D Materials and Applications
- Microfluidic and Bio-sensing Technologies
- Quantum Dots Synthesis And Properties
- Musculoskeletal pain and rehabilitation
Deakin University
2014-2024
Harvard University
2016-2022
University of Michigan
2022
University of California, Los Angeles
2022
Geelong Hospital
2016-2020
State Key Laboratory of Building Safety and Built Environment
2014-2018
Monash University
2012-2018
Regional Centre for Biotechnology
2016
Xavier University
2015
Exploiting the distinct excitation and emission properties of concomitant electrochemiluminophores in conjunction with inherent color selectivity a conventional digital camera, we create new strategy for multiplexed electrogenerated chemiluminescence detection, suitable development low-cost, portable clinical diagnostic devices. Red, green blue emitters can be efficiently resolved over three-dimensional space ECL intensity versus applied potential wavelength. As relative contribution ratio...
Heterogeneous electrochemiluminescence (ECL) assays employing tri-n-propylamine as a co-reactant and tris(2,2′-bipyridine)ruthenium(II) ([Ru(bpy)3]2+) derivative an emissive label are integral to the majority of academic commercial applications ECL sensing. This model system is active research area constitutes basis successfully commercialized bead-based immunoassays. Herein, we propose novel approach enhancement such conventional via incorporation second metal coordination complex,...
Electrochemiluminescence (ECL) microscopy is an emerging technique with new applications such as imaging of single entities and cells. Herein, we have developed a bimodal bicolor approach to record both positive ECL (PECL: light-emitting object on dark background) shadow label-free (SECL: nonemissive shadowing the background luminescence) images This result simultaneous emissions [Ru(bpy)3]2+ used label cellular membrane (PECL) [Ir(sppy)3]3– dissolved in solution (SECL). By spectrally...
Enhancement of the electrochemiluminescence (ECL) tris(2,2′-bipyridine)ruthenium(II) ([Ru(bpy)3]2+) and tri-n-propylamine by redox mediators has emerged as a new approach to maximise sensitivity this mode detection. Herein, we examine influence six water-soluble iridium(III) complexes on widely used ECL system deconvoluting their respective contributions overall intensity over range applied potentials. The interconnected co-reactant these metal complexes, eliciting enhancement or quenching...
We demonstrate the mixed annihilation electrogenerated chemiluminescence of tris(2,2'-bipyridine)ruthenium(ii) with various cyclometalated iridium(iii) chelates. Compared to ECL systems comprising organic luminophores, absence T-route pathways enables effective predictions observed based on simple estimations exergonicity reactions leading excited state production. Moreover, multiple, closely spaced reductions and oxidations metal chelates provide ability finely tune energetics therefore...
Abstract Compared to tris(2‐phenylpyridine)iridium(III) ([Ir(ppy) 3 ]), iridium(III) complexes containing difluorophenylpyridine (df‐ppy) and/or an ancillary triazolylpyridine ligand [3‐phenyl‐1,2,4‐triazol‐5‐ylpyridinato (ptp) or 1‐benzyl‐1,2,3‐triazol‐4‐ylpyridine (ptb)] exhibit considerable hypsochromic shifts (ca. 25–60 nm), due the significant stabilising effect of these ligands on HOMO energy, whilst having relatively little LUMO. Despite their lower photoluminescence quantum yields...
Redox mediated mechanism in electrochemiluminescence (ECL) beads-based assay: the influence of Ir( iii ) redox mediators increases ECL signal up to 107%.
A simple graphical approach to characterise the energetically feasible electrogenerated chemiluminescence (ECL) reaction pathways with tri-<italic>n</italic>-propylamine is discussed.
We examine energy transfer and quenching within annihilation ECL systems comprising mixed metal-complexes in solution, show the dependence of emission intensities on luminophore concentration applied potentials.
The classic and most widely used co-reactant electrochemiluminescence (ECL) reaction of tris(2,2'-bipyridine)ruthenium(ii) ([Ru(bpy)3]2+) tri-n-propylamine is enhanced by an order magnitude fac-[Ir(sppy)3]3- (where sppy = 5'-sulfo-2-phenylpyridinato-C2,N), through a novel 'redox mediator' pathway. Moreover, the concomitant green emission [Ir(sppy)3]3-* enables internal standardisation ECL [Ru(bpy)3]2+. This can be applied using digital camera as photodetector exploiting ratio R B values RGB...
Abstract We examine the electrogenerated chemiluminescence (ECL) of three Ir( ) 2 (acac) complexes, where acac=acetylacetonate anion and =2‐phenylpyridine (ppy), 2‐phenylbenzothiazole (bt), or 2‐phenylquinoline (pq) anions, with tri‐ n ‐propylamine co‐reactant in acetonitrile under a range chemical instrumental conditions; this follows somewhat conflicting recent claims ECL intensities from complexes type. Relevant electrochemical, spectroscopic, properties are evaluated direct comparison...
Incorporating phenylpyridine- and triazolylpyridine-based ligands decorated with methylsulfonate or tetraethylene glycol (TEG) groups, a series of iridium(III) complexes has been created for green blue electrogenerated chemiluminescence under analytically useful aqueous conditions, tri-n-propylamine as coreactant. The relative electrochemiluminescence (ECL) intensities the were dependent on sensitivity photodetector over wavelength range pulse time applied electrochemical potential. In terms...
The annihilation electrogenerated chemiluminescence of mixtures Ir(<sc>iii</sc>) complexes is eliminated by manipulating reduction potentials through subtle changes in ligand structure.
We demonstrate the first use of pure films two-dimensional (2D) transition metal carbides and nitrides (Ti3C2Tx MXene) as an electrode material for electrogenerated chemiluminescence (ECL). The Ti3C2Tx MXene electrodes exhibited excellent electrochemical stability in cathodic scan range produced bright reductive-oxidation ECL using peroxydisulfate a co-reactant with tris(2,2'-bipyridine)ruthenium(ii) ([Ru(bpy)3]2+) luminophore.
This communication describes the use of uncoated cellophane (regenerated cellulose films) for fabrication microplates, and coated open-channel microfluidic devices.
We examined a series of commercially available screen-printed electrodes (SPEs) for their suitability electrochemical and electrogenerated chemiluminescence (ECL) detection systems. Using cyclic voltammetry with both homogeneous solution-based heterogeneous bead-based ECL assay format, the most intense signals were observed from unmodified carbon-based SPEs. Three varieties tested, Zensor outperforming DropSens Kanichi in terms sensitivity. The incorporation nanomaterials electrode did not...
Exploration of potential-dependent, multi-colour co-reactant electrochemiluminescence from multiple luminophores at the working and counter electrodes reveals new pathways to emission.
Electrochemiluminescence (ECL) has emerged as a sensitive analytical technique with wide range of applications. While recent studies have begun to explore the role redox mediators facilitate ECL systems, this work extends these foundational insights by developing comprehensive theoretical framework that supports, generalizes, and rationalizes mechanistic pathways borrowed from molecular electrocatalysis. This advancement is demonstrated through electrocatalytic amplification coreactant...
Abstract Previously dismissed as an unwanted and unpredictable artifact of electrogenerated chemiluminescence (ECL) systems, emission at the counter electrode has new importance in context emerging multicolor potential‐resolved ECL systems which a much wider range potentials are applied working electrode. Herein, we explore annihilation from mixture two electrochemiluminophores both electrodes three‐electrode electrochemical cell. The were measured, simultaneous spatially resolved was...
Digital image analysis of the separation results colorless analytes on thin-layer chromatography (TLC) plates usually involves using specially tailored software to analyze images generated from either a UV scanner or lamp station with digital camera densitometer. Here, low-cost alternative setup for quantitative TLC-digital is demonstrated universal staining reagent (iodine vapor), an office and commonly available (Microsoft Paint) red, green blue colors (RGB values). Urinary creatinine used...
The first highly water soluble, blue-luminescent iridium(<sc>iii</sc>) complex for chemiluminescence detection is presented.