- Bladder and Urothelial Cancer Treatments
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Urinary and Genital Oncology Studies
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Prostate Cancer Treatment and Research
- Urological Disorders and Treatments
- Lung Cancer Research Studies
- Brain Metastases and Treatment
- Lung Cancer Treatments and Mutations
- Ultrasound and Hyperthermia Applications
- Colorectal and Anal Carcinomas
- Cancer Genomics and Diagnostics
- Cancer, Hypoxia, and Metabolism
- Advanced X-ray and CT Imaging
- Metastasis and carcinoma case studies
- Sexual Differentiation and Disorders
- Radiology practices and education
- Advances in Oncology and Radiotherapy
- Genomic variations and chromosomal abnormalities
- Radiation Dose and Imaging
- Dysphagia Assessment and Management
- Reconstructive Surgery and Microvascular Techniques
The Christie NHS Foundation Trust
2021-2024
University of Manchester
2011-2023
Clatterbridge Cancer Centre NHS Foundation Trust
2023
The Christie Hospital
2021-2023
Sheffield Teaching Hospitals NHS Foundation Trust
2022
Lancashire Teaching Hospitals NHS Foundation Trust
2016
Mount Vernon Cancer Centre
2015
Manchester Academic Health Science Centre
2011
Bladder-sparing trimodal therapy (TMT) is an alternative to radical cystectomy (RC) according international guidelines. However, there are limited data guide management of nonmetastatic clinically node-positive bladder cancer (cN+ M0 BCa). We performed a multicenter retrospective analysis survival outcomes in patients inform practice.
To develop a machine learning (ML) model based on radiomic features (RF) extracted from whole prostate gland magnetic resonance imaging (MRI) for prediction of tumour hypoxia pre-radiotherapy.
<h3>Introduction</h3> Despite documented low risk (<1%) of stomal metastases and limited evidence-base, current BSG guidelines advocate a direct puncture approach to gastrostomy in head & neck cancers (HNC).<sup>1</sup> We hypothesised that there would be variation the insertion practices for HNC surveyed hospitals our region aimed retrospectively determine incidence PEG site at centre where pull-through technique is often first line HNC. <h3>Methods</h3> Firstly, an electronic survey...
Abstract We present a newly recognized, likely autosomal recessive, pleiotropic disorder seen in four individuals (three siblings and their nephew) from consanguineous family of Pakistani origin. The condition is characterized by hypogonadotropic hypogonadism, severe microcephaly, sensorineural deafness, moderate learning disability, distinctive facial dysmorphic features. Autozygosity mapping using SNP array genotyping defined single, large autozygous region 13.1 Mb on chromosome 3p21...
The advent of immune checkpoint inhibition has improved survival for patients with recurrent or metastatic platinum-resistant head and neck squamous cell carcinoma (HNSCC). In this setting, nivolumab shown significantly outcomes in comparison to chemotherapy.1 Evidence from pre-clinical studies suggests the addition radiotherapy immunotherapy may improve disease control.2 However, uncertainty remains as whether combination treatment translates clinical setting HNSCC. Currently, decision...