A5036129904- MicroRNA in disease regulation
- Circular RNAs in diseases
- Reproductive System and Pregnancy
- Molecular Biology Techniques and Applications
- Cancer-related molecular mechanisms research
- Pregnancy and preeclampsia studies
- Extracellular vesicles in disease
- COVID-19 Impact on Reproduction
- CRISPR and Genetic Engineering
- Ovarian function and disorders
- Folate and B Vitamins Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Machine Learning in Materials Science
- Nutrition, Genetics, and Disease
- Thyroid Disorders and Treatments
Roskilde University
2022-2025
Zealand University Hospital Køge
2020-2025
Næstved Sygehus
2022
Women with polycystic ovary syndrome (PCOS) often change their metabolic profile over time to decrease levels of androgens while gaining a propensity for the development syndrome. Recent discoveries indicate that microRNAs (miRNAs) play role in PCOS and constitute potential biomarkers PCOS. We aimed identify miRNAs associated an impaired women PCOS, follow-up study, compared without PCOS.Clinical measurements status disease were obtained twice 6 years apart cohort 46 nine controls. All...
Aim Ovarian cancer (OC) is the leading cause of gynecological deaths. Current biomarkers OC are not specific or sensitive enough. Extracellular vesicles (EVs), EV surface proteins and their cargo microRNA (miRNA) show potential as biomarkers. This study aimed to characterize ability EVs identify early OC-biomarkers among blood donors six months before diagnosis. Methods Study groups patients, benign tumor patients (B), healthy (Control), with incident diagnosis within last draw...
Although the vast majority of individuals succumbing to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are elderly, fatality rate (IFR) estimates for age group ≥70 years still scarce. To this end, we assessed SARS-CoV-2 seroprevalence among retired blood donors and combined it national disease 2019 (COVID-19) survey data provide reliable population-based IFR group.We identified 60 926 aged in rosters 3 regionwide Danish banks invited them fill a questionnaire on...
Abstract Disclosure: N.L. Frisk: None. J.R. Shorter: O.B. Pedersen: L.T. Dalgaard: Introduction: While impaired thyroid function leading to subclinical hypothyroidism and overt is common in Denmark, the knowledge about paths by which patients’ progress limited. Undiagnosed as well constitute serious risk factors for development of cardio metabolic disease. The Danish Blood Donor Study (DBDS) a large longitudinal cohort biobank containing information samples dating more than 10 years back....