- Infant Nutrition and Health
- Folate and B Vitamins Research
- Breastfeeding Practices and Influences
- Neonatal Respiratory Health Research
- Child Nutrition and Feeding Issues
- Child Nutrition and Water Access
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Iron Metabolism and Disorders
- Infant Development and Preterm Care
- Obesity, Physical Activity, Diet
- Esophageal and GI Pathology
- Nutritional Studies and Diet
- Pregnancy and preeclampsia studies
- Clinical Nutrition and Gastroenterology
- Digestive system and related health
- Diet and metabolism studies
- Nutrition and Health in Aging
- Metabolism and Genetic Disorders
- Pregnancy and Medication Impact
- Gut microbiota and health
- Fatty Acid Research and Health
- Maternal Mental Health During Pregnancy and Postpartum
- Hemoglobinopathies and Related Disorders
- Viral gastroenteritis research and epidemiology
Hospital for Sick Children
2016-2025
University of Toronto
2016-2025
Mount Sinai Hospital
2017-2025
SickKids Foundation
2013-2024
Sinai Health System
2018-2024
Bank of Canada
2019-2024
University of Oxford
2024
Program for Appropriate Technology in Health
2021
Seattle University
2021
Hôpital de l'Enfant-Jésus
2021
Objectives. A randomized, masked, controlled trial was conducted to assess effects of supplementing premature infant formulas with oils containing the long-chain polyunsaturated fatty acids, arachidonic acid (AA; 20:4n6), and docosahexaenoic (DHA; 22:6n3) on growth, visual acuity, multiple indices development. Methods. Infants (N = 470) birth weights 750 1800 g were assigned within 72 hours first enteral feeding 1 3 formula groups or without acids: 1) control 144), 2) AA+DHA from fish/fungal...
<h3>Background</h3> Low folate concentrations are inversely associated with birth defects, including neural tube congenital heart disease and oral clefts. Conversely, high may be adverse outcomes, increased risk of colorectal cancer among those pre-existing neoplasms. The purpose our study was to investigate the status a nationally representative sample Canadians, subset women childbearing age. <h3>Methods</h3> We examined red blood cell members general population aged 6–79 years (<i>n</i> =...
Folate, an essential nutrient found naturally in foods a reduced form, is present dietary supplements and fortified oxidized synthetic form (folic acid). There widespread agreement that maintaining adequate folate status critical to prevent diseases due inadequacy (e.g., anemia, birth defects, cancer). However, there are concerns of potential adverse effects excess folic acid intake and/or elevated status, with the original concern focused on exacerbation clinical vitamin B-12 deficiency its...
Two complementary studies focused on stability of infant temperament across the 1st year and considered age, gender, birth order, term status, socioeconomic status ( SES ) as moderators. Study 1 consisted 73 mothers firstborn girls boys queried at 2, 5, 13 months age. 2 335 infants different 6 12 months. Consistent positive negative affectivity factors emerged all time points both studies. Infant proved stable robust . Stability coefficients for scales were medium to large shorter (< 9...
In a recent meta-analysis, human milk feeding of low birth-weight (LBW) infants was associated with 5.2 point improvement in IQ tests. However, the studies this regimens were used (unfortified milk, term formula) that no longer represent recommended practice.To compare growth, in-hospital tolerance, morbidity, and development (cognitive, motor, visual, language) LBW fed different amounts until chronologic age (CA) those nutrient-enriched formulas from first enteral feeding.The data study...
OBJECTIVES. The purpose of this pilot study was to determine whether mixing a multinutrient fortifier approximately one half the human milk fed each day for finite period after discharge improves nutrient intake and growth predominantly milk–fed low birth weight infants. We also assessed impact intervention on exclusivity feeding. METHODS. Human (≥80% feeding per day) (750–1800 g) infants (n = 39) were randomly assigned at hospital either control or an group. Infants in group discharged from...
We followed 16 patients with a variety of mitochondrial diseases over one to four periods treatment (2 months each) coenzyme Q<sub>10</sub> plus vitamins K<sub>3</sub> and C, riboflavin, thiamine, niacin, using independent measures oxidative metabolism assess efficacy. There were large (<threefold) increases in serum concentrations treatment, but no measure showed significant improvement for the group, nor did any individual patient show significant, reproducible, objective clinical...
Human milk (HM) is the optimal source of nutrition for premature infants; however, it unclear whether HM alone sufficient to meet their elevated nutritional requirements early after hospital discharge. We previously reported that infants (750-1800 g birth weight) fed containing extra nutrients 12 weeks discharge had dietary intakes closer recommended levels and grew more rapidly than those alone. The objectives present article are examine impact this intervention on bone mineralization, body...