A5001227982- Fungal Infections and Studies
- Infectious Diseases and Mycology
- Pneumocystis jirovecii pneumonia detection and treatment
- Cytomegalovirus and herpesvirus research
- Antifungal resistance and susceptibility
- Hematopoietic Stem Cell Transplantation
First Affiliated Hospital of Fujian Medical University
2024
Fujian Medical University
2022-2024
Union Hospital
2022
Cytomegalovirus reactivation (CMVr) and bloodstream infections (BSI) are the most common infectious complications in patients after allogeneic haematopoietic stem cell transplantation (allo-HSCT). Both associated with great high morbidity whilst BSI is leading cause of mortality. This retrospective study evaluated incidence CMVr BSI, identified risk factors, assessed their impact on survival allo-HSCT recipients during first 100 days transplantation. The comprised 500 who were CMV...
Patients with hematological malignancies (HM) often develop the invasive fungal disease (IFD), causing important morbidity/mortality. While treatment guidelines are available, risk stratification models for optimizing antifungal therapy strategies few. Clinical records from 458 HM patients IFD were retrospectively analyzed. Following Chinese guidelines, received empirical (n = 239) or diagnostic-driven 219). The effectiveness rate was 87.9% and 81.7% groups (P ≥ 0.05). incidence of adverse...