H.K.A. Premachandra

ORCID: 0000-0001-6469-2083
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About
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Research Areas
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Genetic diversity and population structure
  • Invertebrate Immune Response Mechanisms
  • Genetic and phenotypic traits in livestock
  • Fish Ecology and Management Studies
  • Identification and Quantification in Food
  • Marine Bivalve and Aquaculture Studies
  • interferon and immune responses
  • Genetic Mapping and Diversity in Plants and Animals
  • Immune Response and Inflammation
  • MicroRNA in disease regulation
  • Ichthyology and Marine Biology
  • Cell death mechanisms and regulation
  • Parasite Biology and Host Interactions
  • Physiological and biochemical adaptations
  • Environmental Toxicology and Ecotoxicology
  • Marine Biology and Environmental Chemistry
  • Crustacean biology and ecology
  • Fish Biology and Ecology Studies
  • Cytokine Signaling Pathways and Interactions
  • Protein Hydrolysis and Bioactive Peptides
  • Parasites and Host Interactions
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Hemoglobinopathies and Related Disorders

University of the Sunshine Coast
2017-2024

University of Peradeniya
2017

Jeju National University
2012-2016

Genomic prediction using Diversity Arrays Technology (DArT) genotype by sequencing platform has not been reported in yellowtail kingfish (Seriola lalandi). The principal aim of this study was to address knowledge gap and assess predictive ability genomic Best Linear Unbiased Prediction (gBLUP) for traits commercial importance a population comprising 752 individuals that had DNA sequence phenotypic records growth (body weight, fork length condition index). gBLUP method used due its...

10.1186/s12864-018-4493-4 article EN cc-by BMC Genomics 2018-01-30

The genetic resources available for the commercially important fish species Yellowtail kingfish (Seriola lalandi) are relative sparse. To overcome this, we aimed 1) to develop a linkage map this species, and 2) identify markers/variants associated with economically traits in (with an emphasis on body weight). Genetic genomic analyses were conducted using 13,898 Single Nucleotide Polymorphism (SNPs) generated from new high through-put genotyping by sequencing platform, Diversity Arrays...

10.3389/fgene.2018.00127 article EN cc-by Frontiers in Genetics 2018-04-17

Abstract Captive breeding programs and aquaculture production have commenced worldwide for the globally distributed yellowtail kingfish ( Seriola lalandi ), captive bred fingerlings are being shipped from Southern Hemisphere to be farmed in Northern Hemisphere. It was recently proposed that Pacific S . comprise at least three distinct species diverged more than 2 million years ago. Here, we tested hypothesis of different “species” using novel genomic data (namely single nucleotide...

10.1038/s41598-017-07419-x article EN cc-by Scientific Reports 2017-08-18

Wildlife diseases are major players in local and global extinctions. Effective disease surveillance, management conservation strategies require accurate estimates of pathogen prevalence. Yet detection wild animals remains challenging. Current gold standards often samples collected through veterinary examination, but this method is costly, intensive, invasive, requires specialised staff equipment. Collection non-invasive samples, such as scats, an effective monitoring tool which can be...

10.1038/s41598-024-76873-1 article EN cc-by-nc-nd Scientific Reports 2024-12-05

Aquaculture mollusc production is predominantly from Asia, with more than 80% of the total biomass produced in China. Vietnam’s annual growing rapidly but comparatively small given its coastal resources. A significant challenge for future production, and oysters particular, supply high-quality spat. Most spat Vietnam comes local wild sources or imported Particularly case oysters, where collection low importation oyster into other jurisdictions not controlled, unreliable presents a...

10.3389/fmars.2023.1161009 article EN cc-by Frontiers in Marine Science 2023-11-17

Abstract Grouper aquaculture around Asia is impacted by the nervous necrosis virus (NNV) and, in response, host resistance to this infection being considered as a trait for selection. However efficient selection may be confounded if there are different genetic strains of NNV within and between regions over years. This study uses statistical approaches assessment “characteristic attributes” (i.e. nucleotide positions that discriminate among strains) assess whether published new RNA2 cds...

10.1038/s41598-017-11263-4 article EN cc-by Scientific Reports 2017-08-31

In recent decades, developing countries with traditionally strong links aquaculture have adopted genetic improvement programs for newly domesticated and captively bred species. Accurate genealogical pedigree information is an essential tool efficient successful this type of was obtained by separate rearing families physical tagging the animals. More recently, molecular based pedigrees (e.g. using SNPs) becoming a potential option, which also may permit communal at stage earlier than usual,...

10.1016/j.aqrep.2021.100615 article EN cc-by Aquaculture Reports 2021-01-29

Cathepsins are lysosomal/cysteine proteases belong to papain family (C1 family) that is involved in intracellular protein degradation, antigen processing, hormone maturation, and immune responses. In this study, member of cathepsin was identified from Manila clam (Mc-Cathepsin D) investigated the response against brown ring disease (BRD) causing Vibrio tapetis challenge. The Mc-Cathepsin D gene encodes characteristic features typical for including eukaryotic viral aspartyl protease signature...

10.9710/kjm.2013.29.2.155 article EN The Korean Journal of Malacology 2013-06-30
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