A5055342332- Reproductive Biology and Fertility
- Birth, Development, and Health
- Biochemical and biochemical processes
- Essential Oils and Antimicrobial Activity
- Regulation of Appetite and Obesity
- Ginseng Biological Effects and Applications
- Apelin-related biomedical research
- Ovarian function and disorders
- Medicinal Plants and Neuroprotection
- Pharmacological Effects of Natural Compounds
- Adipokines, Inflammation, and Metabolic Diseases
- Toxin Mechanisms and Immunotoxins
University of Madras
2022-2025
Coir pith, an agro-industrial residue, is resistant to natural degradation, and its accumulation causes environmental pollution. Ferulic acid, a precursor of vanillin, was extracted from the raw coir pith by chemical pre-treatment such as alkaline hydrolysis, acidification, liquid-liquid extraction method. The obtained ferulic acid (1.2 g/50 g) analysed using high-performance liquid chromatography (HPLC) used substrate for biotransformation Aspergillus niger vanillic which, in turn,...
In cervical cancer chemotherapy, paclitaxel (PTX) chemoresistance has become a major difficulty, and it also affects the survival rate of numerous tumor patients. Thus, for reversal chemoresistance, is imperative to develop combinatory drugs with petite or almost no side effects sensitize cells paclitaxel. Ginsenoside Rg5 (GRg5) may act as chemosensitizer by reversing multidrug resistance. The present study aimed determine potential GRg5 in PTX-resistant human adeno-carcinoma cell lines...
Pituitary gonadotropins directly govern ovarian functions, which are in turn regulated by the steroid hormones. The precise interplay of and hormones is critical for follicle growth differentiation. Furthermore, autophagy regulates However, how high-fat-high fructose (HFD-HF) diet facilitates autophagy-mediated follicular differentiation ovary obscure. We fed prepubertal rats (PND 25) an HFD-HF until PND 90. results showed diminished adenohypophyseal GnRHR, PR, aromatase expression, whereas...
Obesity-related disruptions in female reproduction are a growing concern. The neuroendocrine regulation of the context obesity involves intricate interplay between adipokines and Hypothalamus-Pituitary- Ovarian (HPO ) axis. In this review, we explore role adipokines, particularly leptin adiponectin, regulating obesity. Leptin, primarily produced by adipocytes, plays pivotal signaling energy status to brain. However, excessive levels can lead resistance, affecting HPO axis causing menstrual...