This study investigated associations between objectively measured physical activity (PA) with sarcopenia and sarcopenic obesity in older British men. Participants were men aged 70-92years (n=1286) recruited from UK Primary Care Centres. Outcomes included (i) sarcopenia, defined as low muscle mass (lowest two fifths of the mid-upper arm circumference distribution) accompanied by muscular strength (hand grip <30kg) or performance (gait speed≤0.8m/s); (ii) severe required all three conditions;...

Of all age groups, older adults spend most of the time sitting and are least physically active. This sequential, mixed-methods feasibility study used a randomised controlled trial design to assess methods for trialling habit-based intervention displace adults' sedentary behaviour with light activity explore impact on behavioural outcomes. Eligibility criteria were 60–74 years, retired, ≥6 h/day leisure sitting. Data collected across four sites in England. The comprised booklet outlining 15...

In the present study, we investigated how overall and specific domains of physical activity sedentary behavior at age 7 years were associated with cognition 11 in 8,462 children from Millennium Cohort Study. Data collected 2001 to 2013. Participation reported. Activity levels also measured objectively. Cognition was assessed using British Ability Scales. General linear models used assess longitudinal associations behavior, both objectively via self-report, cognition. Analyses adjusted for...

The aim of this study is to investigate whether mothers' perception distance from home green/open spaces associated with their child's screen time.We used mother-reported data sweep six (2010-2011) the Growing Up in Scotland (n=3586 children aged 5.9yrs) examine associations between walking space and time (TV viewing time/computer use). Analyses were adjusted for age, sex other pre-specified covariates, including sport/exercise participation, mental general health, birth weight, parental...

The effects of replacing time in specific activity categories for other (e.g. sedentary with light activity) on health and fitness are not well known. This study used isotemporal substitution to investigate the substituting an equal exchange fashion young people. Participants were drawn from schools Camden, London (n = 353, mean age 9.3 ± 2.3 years). Time sedentary, moderate-to-vigorous (MVPA) was measured via accelerometry. (sedentary, MVPA) equivalent another category examined using...

This study aimed to investigate whether active outdoor play and/or sports at age 10 is associated with sport/physical activity 32 year follow-up using a birth cohort study.Data were from the 1970 British Cohort Study, longitudinal observational study. The present paper included data years and 42 surveys. At participant's mother provided information regarding how often their child played sports, outside on streets, parks or playgrounds. participants reported frequency of participation in...

Adaptation of physical activity self-report questionnaires is sometimes required to reflect the behaviours diverse populations. The processes used modify though are typically underreported. This two-phased study a formative approach investigate validity and reliability Physical Activity Questionnaire for Adolescents (PAQ-A) in English youth. Phase one examined test content response process subsequently informed modified version PAQ-A. two assessed PAQ-A.In phase one, focus groups (n = 5)...

The physical school environment is a promising setting to increase children's activity although robust evidence sparse. We examined the effects of major playground reconstruction on and sedentary time in primary schools using quasi-experimental design (comparison group pre-test/post-test design).Five experimental two control from deprived areas inner city London were recruited at baseline. Main outcome was measured objective monitoring (Actigraph accelerometer) one year follow up. Pupils'...

Introduction It is well established that physical activity (PA) protects against mortality and morbidity, but how long-term patterns of PA are associated with cardiovascular disease (CVD) remains unclear. Methods 3231 men recruited to the British Regional Heart Study, a prospective cohort study, reported usual levels at baseline in 1978–1980 (aged 40–59 years) 12-year, 16-year 20-year follow ups. Twenty-year trajectories PA, spanning from 1978/1980 2000, were identified using group-based...

Time spent outdoors is associated with higher levels of physical activity. To date, correlates independent outdoor play have not been investigated. This study aimed to identify potential demographic, behavioural, environmental and social children's play. Data were from the Millennium Cohort Study when children aged 7 years. Parents reported whether their played out unsupervised (yes/no) as well above mentioned Children's activity measured using waist worn accelerometry. Multiple logistic...

Maintenance of physical activity (PA) during later life is associated with optimal health; however, the long-term trajectories PA into old age and their predictors have not been extensively researched using latent class methods. This study aimed to identify self-reported in men transitioning from midlife age. 7735 (aged 40–59 years) recruited 1978–80 were followed up after 12, 16 20 years, reporting PA, health status, lifestyle behaviours socio-demographic characteristics. Group-based...

Abstract Purpose Alopecia areata (AA) is an autoimmune-mediated inflammatory dermatological disease characterised by non-scarring hair loss affecting the scalp and sometimes other hair-bearing sites. This study aimed to elicit health state utility values (HSUVs) from UK general population for AA using time trade off (TTO) interviews. Methods Vignette descriptions of states defined extent were developed (as well as one describing caregiver burden). These data standardised patient reported...

Elite athletes should have little concern about meeting recommended guidelines on physical activity. However, sedentary behaviour is considered a health risk independent of activity, and recognised in public advising against prolonged time. There has been very research athletes' activity outside elite sport.Given performance links, we investigated in-season post-training levels 28 professional footballers during the English Premiership season. Players volunteered to wear triaxial wrist...

The present study aimed to explore patient preferences for attributes of advanced hepatocellular carcinoma (HCC) treatments. A stated preference survey was completed by 150 patients with HCC living in Europe. Overall survival (OS) the most important attribute, closely followed risk diarrhea and hypertension, other adverse event (AE) risks. Patients were willing trade OS reduce AE While less than AEs, also preferred shorter waiting times, one-off administration selective internal radiation...

This study aims to examine the tracking and predictability of physical activity in old age from overall participation sport, recreational walking mid-life. Prospective population-based cohort study. British Regional Heart Study participants recruited primary care centres UK 1978-1980. Men (n=3413) self-reported their at baseline, 12, 16 20-year follow-ups were categorised as inactive or active having high low activities. Tracking was assessed using kappa statistics random effects models....

The aim of the study was to determine whether objectively measured daily physical activity and posture sitting, standing, sit-to-stand transitions are associated with assessments affect.Participants (N = 51, 49% female) wore ActivPal accelerometers for 24 h/d seven consecutive days. Time spent being physically active were derived each day. Participants also completed a mood inventory evening. Multilevel models examined within- between-person associations positive negative affect, adjusting...

The trajectories of physical activity (PA) from midlife into old age and their associations with established novel cardiovascular disease (CVD) risk factors in later life remain unclear. This study examined between 20-year nonoccupational PA a range CVD biomarkers at ages 60-79 years. We used data sample 3,331 men (mean baseline = 50.2 ± 5.8 years) recruited 1978-1980, follow-up after 12, 16, 20 years, reporting habitual each wave. At the follow-up, surviving attended examination provided...

Background: To investigate whether light exposure was associated with objectively measured physical activity (PA) and sedentary behaviour in young people. Methods: Participants (n = 229, 46.7% female) were people (mean 8.8 years [SD ± 2.2]) from the borough of Camden, UK. Daily time, moderate vigorous PA (MVPA) using a tri-axial accelerometer an ambient sensor during summer. Multiple linear regression models examined associations between average daily exposure, time MVPA. Models repeated...

This study investigated the association of travel mode to school and non-school destinations with objectively assessed health markers physical activity in an ethnically diverse sample inner-city UK schoolchildren. We used data from Camden Active Spaces project (n = 450 children aged 9.1 yrs) examine associations frequency active daily out-of-school activity, sedentary time markers; whilst controlling for appropriate covariates including measured route length. High was associated more...

One important determinant of childhood physical activity and sedentary behavior may be that motor development in infancy. The present analyses aimed to investigate whether gross fine delays infants were associated with objective self-reported childhood. Data from the UK Millennium Cohort Study, a prospective cohort study, involving children born on or around millennium (September 2000 January 2002). When 9 months old, parents reported children's motor-coordination, at 7 years, sports club...

This update describes changes to procedures for our randomised controlled trial of ‘On Your Feet Earn Seat’, a habit-based intervention reduce sedentary behaviour in older adults. Some the amendments have arisen from addition new sites, each offering different possibilities and constraints study procedures. Others been made response problems encountered administering intended recruitment at London sites described original protocol. All received ethics governance clearance, were before or...

Background: This study estimated utility values for non-alcoholic steatohepatitis (NASH). Previous studies have assumed that health-related quality of life does not vary between the early stages NASH. Materials &amp; Methods: Discrete choice experiment (DCE) surveys value avoiding fibrosis progression. Patients also completed EQ-5D-5L. Marginal rates substitution change associated with Results: DCE were by UK general public (n = 520) and patients NASH 154). The decline F1 F4 decompensated...