- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Dermatology and Skin Diseases
- Essential Oils and Antimicrobial Activity
- Graphene and Nanomaterials Applications
- Ocular Surface and Contact Lens
- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Polymer Surface Interaction Studies
- Anesthesia and Neurotoxicity Research
- Computational Drug Discovery Methods
- Neuroscience and Neural Engineering
- Biosimilars and Bioanalytical Methods
- Antifungal resistance and susceptibility
- Molecular Communication and Nanonetworks
- 3D Printing in Biomedical Research
- Hydrogels: synthesis, properties, applications
- Surface Modification and Superhydrophobicity
Manipal Academy of Higher Education
2020-2025
Abstract: Artificial intelligence (AI) is a rapidly transforming drug discovery and development process, significantly impacting the pharmaceutical industry enhancing human health. This review article examines tremendous role of AI in analyzing complex biological data, optimizing research processes, reducing costs production. Implementation sector can store vast dataset manufacturing identify potential disease targets, simulate physiological conditions, predict interactions. The also...
Abstract The current study aims to establish a novel ultra-deformable vesicular system enhance the drug penetration across skin by preparing ketoconazole-loaded menthosomes. It was achieved through regular thin-film evaporation & hydration techniques. To examine effect of formulation parameters on menthosome characteristics, 2 3 full factorial design used using Design-Expert® software. optimized batch exhibited vesicle size (107.6 nm), polydispersity index (PDI) (0.248), entrapment...
Objective: The study aimed to use a quality-by-design approach screen out the most suitable process and formulation parameters for developing antifungal drug-loaded pegylated bilosomes. Methods: Thin film hydration technique was used prepare formulations. A design experiment [Design Expert® software; Design of Experiments (DOE)] employing two levels at three factors conduct eight runs select variables. It assessed different response variables, such as Particle Size (PS), Polydispersity Index...
Objective: The study aimed to develop and optimize cromolyn sodium-based ocular in situ gel improve the ophthalmic contact period provide sustained drug release for treating allergic conjunctivitis. Methods: Formulations were prepared using sodium alginate HPMC K4M (Hydroxypropyl Methylcellulose) polymers characterized evaluated viscosity, gelling time, vitro release, optimized a factorial 32 DOE design (Version 11; Design Expert® software). resulting formulation was tested hyperemia...