A5041960834- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Colorectal Cancer Treatments and Studies
- Esophageal and GI Pathology
- Trauma Management and Diagnosis
- Gastrointestinal Tumor Research and Treatment
- Traumatic Ocular and Foreign Body Injuries
- Airway Management and Intubation Techniques
- Congenital Diaphragmatic Hernia Studies
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Anorectal Disease Treatments and Outcomes
- Pleural and Pulmonary Diseases
- Metastasis and carcinoma case studies
- Vascular Anomalies and Treatments
- Teratomas and Epidermoid Cysts
- Foreign Body Medical Cases
- Gastrointestinal Bleeding Diagnosis and Treatment
- Head and Neck Anomalies
- Streptococcal Infections and Treatments
- Thyroid Cancer Diagnosis and Treatment
Cho Ray Hospital
2015-2024
Kyoto University
2000
Meharry Medical College
1990
The phase III ADAURA (ClinicalTrials.gov identifier: NCT02511106) primary analysis demonstrated a clinically significant disease-free survival (DFS) benefit with adjuvant osimertinib versus placebo in EGFR-mutated stage IB-IIIA non-small-cell lung cancer (NSCLC) after complete tumor resection (DFS hazard ratio [HR], 0.20 [99.12% CI, 0.14 to 0.30];
Adjuvant chemotherapy is recommended in patients with resected stages II to IIIA (and select IB) NSCLC; however, recurrence rates are high. In the phase 3 ADAURA study (NCT02511106), osimertinib was found have a clinically meaningful improvement disease-free survival (DFS) IB EGFR-mutated (EGFRm) NSCLC. Here, we report prespecified and exploratory analyses of adjuvant use outcomes from ADAURA.Patients EGFRm NSCLC were randomized 1:1 receive or placebo for years. before randomization not...
Abstract Purpose: In the phase III ADAURA trial, adjuvant treatment with osimertinib versus placebo, with/without prior chemotherapy, resulted in a statistically significant and clinically meaningful disease-free survival benefit completely resected stage IB–IIIA EGFR-mutated (EGFRm) non–small cell lung cancer (NSCLC). We report health-related quality of life (HRQoL) outcomes from ADAURA. Patients Methods: randomized 1:1 received oral 80 mg or placebo for 3 years until...
Subjects and method: A total of 164 patients were diagnosed with blunt thoracic trauma (BTT) associated rib fractures between October 2020 2023 at Viet Duc Friendship Hospital, Cho Ray Tiep Hospital. The study population was divided into two groups: Group 1: Patients BTT who underwent fixation surgery using plates screws. 2: did not undergo (conservative treatment). This is a multicenter descriptive longitudinal follow-up, including non-randomized control group. Results: More than 3/4 male...
Congenital tracheal malformations are less common than congenital cardiac diseases and surgical repair of these anomalies is complex. We sought to examine the treatment outcomes in cases presenting with or without associated malformations.We retrospectively reviewed demographic, clinical, imaging data 49 children who underwent surgery for between August 2013 September 2017. Data were collected from hospital records.In all, patients (male, 30; female, 19) surgeries at our center. The ages 3...
The present descriptive study shares the overall experience of treating all these patients where different surgical process was adopted depending on treatment required after carefully evaluating risk factors and comorbidities.The conducted at Department Thoracic Surgery, Choray Hospital, Vietnam between period 2010 to 2020. We have treated 95 altogether in this duration.We were able save most by applying thoracotomy thoracic irrigation for based observed indications that identified...
Esophageal perforation is a life-threatening condition associated with high mortality and morbidity. Ambiguous clinical presentation one of the most common causes delayed difficult diagnosis esophageal perforation. In this retrospective single-center study, we reviewed outcome primary closure in patients between 2009 2017.The data 65 attending our department thoracic surgery (from to 2017) for were reviewed. Primary repair was attempted 63 irrespective site time interval injury hospital...
Hintergrund Osimertinib ist ein EGFR-TKI der 3. Generation, sensitivierende und EGFR-T790M-Resistenzmutationen potent selektiv hemmt. wirksam bei EGFRm NSCLC, einschließlich ZNS-Metastasierung. In Primäranalyse Phase-III-Studie ADAURA (NCT02511106) zeigte die adjuvante Gabe von einen signifikanten klinisch bedeutsamen Vorteil im krankheitsfreien Überleben (DFS) gegenüber Placebo (PBO) Patienten mit R0-reseziertem (Ex19del/L858R) NSCLC,±adj. Chemotherapie (CT): Stadium II–IIIA DFS HR, 0,17;...
Aim Post-tuberculosis tracheobronchial stenosis is rare but one of the most dangerous complications tuberculosis. Balloon dilatation, stent insertion, laser photoresection, argon plasma coagulation, and cryotherapy are some initial treatments recommended for mild to moderate cases. Here, we report a case series patients who underwent segmental resection end-to-end anastomosis bronchial sliding technique severe long-segment tracheal stenosis. Methods We retrospectively reviewed medical...
Abstract Background Recent developments in robotic technology have brought significant changes video-assisted thoracoscopic surgery (r-VATS) worldwide, particularly including the treatment thorax for mediastinal, esophagus, and pulmonary lesions. Currently, there are only a few reports describing procedural experience outcomes with r-VATS. The objective of this study is to provide our initial using r-VATS at single center, specific attention safety, efficacy, details. Methods We...
Background Volatile anesthetic agents have been shown to contractile effects in vascular tissues during specific conditions. This study compared of halothane and sevoflurane rat aorta treated with verapamil. also tried elucidate the mechanism contraction. Methods Endothelium-denuded thoracic was used for recording isometric tension measurement influx 45Ca2+. All experiments were performed presence In tension, rings precontracted a submaximum dose phenylephrine, followed by exposure or...
Supplementary Figure from Health-Related Quality of Life Outcomes in Patients with Resected Epidermal Growth Factor Receptor–Mutated Non–Small Cell Lung Cancer Who Received Adjuvant Osimertinib the Phase III ADAURA Trial
Background: Evidence for the efficacy of surgical stabilization rib fractures in patients with is controversial. Objective: We aim to compare clinical outcomes fixation fracture non-operative treatment. Methods: Our institutional database from three general hospitals (Viet Duc Hospital, Viet Tiep Friendship Hospital & Cho Ray Hospital) was queried identify flail chest treated locked plate between December 2021 and February 2023. A medical record review demographic, injury, hospital, data...
Mục tiêu: Đánh giá kết quả sớm phẫu thuật nội soi lồng ngực có robot hỗ trợ (robotic assisted thoracoscopic surgery - RATS) điều trị u tuyến ức tại Bệnh viện Chợ Rẫy. Phương pháp nghiên cứu: Nghiên cứu can thiệp, tiến cứu, không đối chứng trên 43 bệnh nhân (BN) được bằng RATS từ tháng 01/2020 12/2023 Khoa Ngoại Lồng ngực, Kết quả: Tuổi trung bình là 49,42 13,46, tỷ lệ nữ/nam 1,39. Tỷ nhược cơ 44,2%, trong đó, 4 ca nhóm I, 11 IIA và IIB. Đường tiếp cận qua mũi chiếm cao nhất (58,1%), bên phải...
Endobronchial tumors, though relatively uncommon, present a diverse array of pathological conditions, including both benign and malignant neoplasms. This retrospective study focuses on the surgical management seven such cases affecting main or lobar bronchi. The involves patient population, ranging in age from 18 to 65 years, with median 26 years. include male female individuals, indicating presence these tumors across various demographics. We carried out interventions remove tumor while...
Mục tiêu: Nhận xét một số đặc điểm lâm sàng, hình ảnh cắt lớp vi tính lồng ngực và mô bệnh học nhân u tuyến ức được điều trị bằng phẫu thuật nội soi có robot hỗ trợ tại Bệnh viện Chợ Rẫy. Đối tượng phương pháp nghiên cứu: Các từ tháng 1/2020 đến 12/2023 khoa Ngoại Lồng Ngực, Kết quả: Tỷ lệ nữ : nam 1,39. Tuổi trung bình là 49,42 ± 13,46 (17-72. nhược cơ 44,2%, trong đó 4 ca nhóm I, 11 IIA IIB. Có 22 BN (51,2%) kích thước khối ≥ 5cm 21 (48,8%) < 5cm, 5,08 3,74 cm. ở vị trí tâm lớn nhất...
Background The stability of the pectus bar is an important determinant success excavatum repair surgery. In practice, several different types fixation method are in use for stabilizing bars. aim this study was to compare performance bridge system with previous systems Methods We performed a retrospective review 1760 cases conducted Thoracic Department Choray Hospital and its satellite hospitals, between 2007 2017. compared results 560 patients who had 1200 other techniques. Results 2 bars...